Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 4/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5443619 | 0.85 | AKT2 (0.52) | AKT2AKT1 | |
| SCHEMBL5458454 | 0.85 | TP53 (0.44) | AKT2AKT1KMT2ARAB9ANPC1 | |
| SCHEMBL5317129 | 0.83 | AKT1 (0.48) | AKT2CNR1AKT1KMT2ARAB9A | |
| SCHEMBL5335616 | 0.81 | AKT1 (0.45) | AKT2AKT1RAB9ANPC1MAPT | |
| SCHEMBL5341397 | 0.81 | AKT1 (0.45) | AKT2AKT1RAB9ANPC1MAPT | |
| SCHEMBL5340360 | 0.79 | AKT1 (0.46) | AKT2AKT1RAB9ANPC1MAPT | |
| SCHEMBL5338301 | 0.74 | AKT1 (0.48) | AKT2AKT1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5335061 | 0.74 | AKT1 (0.42) | AKT2AKT1RAB9ANPC1MAPT | |
| SCHEMBL5341020 | 0.74 | AKT1 (0.50) | AKT2CNR1AKT1 | |
| SCHEMBL5336859 | 0.73 | CNR1 (0.46) | AKT2CNR1AKT1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |