Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.46 |
| ▸ | AKT1 | P31749 | 4/20 | 0.41 |
| ▸ | AKT2 | P31751 | 3/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5343515 | 0.93 | CNR1 (0.48) | CNR1AKT1AKT2DGAT2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5348937 | 0.88 | CNR1 (0.56) | CNR1AKT1AKT2TRPA1 | |
| SCHEMBL5317129 | 0.85 | AKT1 (0.48) | CNR1AKT1AKT2NPC1RAB9A | |
| SCHEMBL5340780 | 0.81 | AKT1 (0.59) | AKT1AKT2ALDH1A1HPGD | |
| SCHEMBL5338301 | 0.77 | AKT1 (0.48) | AKT1AKT2NPC1RAB9A | |
| SCHEMBL5317976 | 0.75 | AKT1 (0.47) | CNR1AKT1AKT2CNR2 | |
| SCHEMBL5337517 | 0.75 | CNR1 (0.50) | CNR1CNR2 | |
| SCHEMBL5342475 | 0.74 | AKT1 (0.59) | AKT1AKT2 | |
| SCHEMBL5333928 | 0.74 | CNR1 (0.58) | CNR1AKT1AKT2ALDH1A1 | |
| SCHEMBL5458903 | 0.73 | AKT2 (0.48) | CNR1AKT1AKT2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |