Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 6/20 | 0.48 |
| ▸ | AKT2 | P31751 | 5/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | CDH1 | P12830 | 1/20 | 0.39 |
| ▸ | APC | P25054 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317129 | 0.92 | AKT1 (0.48) | AKT1AKT2CTRCEGLN1CDH1 | |
| SCHEMBL5342400 | 0.90 | AKT1 (0.50) | AKT1AKT2CTRCEGLN1CDH1 | |
| SCHEMBL5343284 | 0.88 | AKT1 (0.53) | AKT1AKT2CTRCCDH1APC | |
| SCHEMBL5342475 | 0.85 | AKT1 (0.59) | AKT1AKT2 | |
| SCHEMBL5343515 | 0.85 | CNR1 (0.48) | AKT1AKT2NPC1RAB9A | |
| SCHEMBL5341020 | 0.82 | AKT1 (0.50) | AKT1AKT2 | |
| SCHEMBL5336859 | 0.77 | CNR1 (0.46) | AKT1AKT2NPC1RAB9A | |
| SCHEMBL5340780 | 0.77 | AKT1 (0.59) | AKT1AKT2KDM4E | |
| SCHEMBL5318498 | 0.76 | AKT1 (0.48) | AKT1AKT2 | |
| SCHEMBL5343937 | 0.75 | CDH1 (0.46) | AKT1AKT2CDH1APCCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |