Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.57 |
| ▸ | NPC1 | O15118 | 10/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPY2R | P49146 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5467434 | 0.91 | GAA (0.55) | RAB9ANPC1SMN1; SMN2GAANPSR1 | |
| SCHEMBL5453449 | 0.85 | NPC1 (0.56) | RAB9ANPC1SMN1; SMN2GAANPSR1 | |
| SCHEMBL5458175 | 0.84 | S1PR1 (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5465662 | 0.82 | NPC1 (0.59) | RAB9ANPC1SMN1; SMN2GAANPSR1 | |
| SCHEMBL5465646 | 0.80 | NPY2R (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5464797 | 0.78 | MEN1 (0.65) | RAB9ANPC1SMN1; SMN2GAANPSR1 | |
| SCHEMBL5451242 | 0.77 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2GAANPSR1 | |
| SCHEMBL15818617 | 0.76 | KDM4E (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5470991 | 0.76 | GAA (0.54) | RAB9ANPC1SMN1; SMN2GAANPSR1 | |
| SCHEMBL5473571 | 0.75 | TRPV1 (0.49) | RAB9ANPC1SMN1; SMN2NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | RAB9A 1528/4885NPC1 1089/4885SMN1; SMN2 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.