Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29659002 | 0.85 | KDM4E (0.46) | L3MBTL1TDP1KDM4EALDH1A1MAPK1 | |
| SCHEMBL22980911 | 0.85 | KDM4E (0.46) | L3MBTL1TDP1KDM4EALDH1A1MAPK1 | |
| SCHEMBL5467693 | 0.83 | AR (0.49) | L3MBTL1TDP1KDM4EALDH1A1MAPK1 | |
| SCHEMBL5468175 | 0.81 | AR (0.56) | L3MBTL1TDP1KDM4EALDH1A1MAPK1 | |
| SCHEMBL5467791 | 0.81 | AR (0.59) | L3MBTL1TDP1KDM4EALDH1A1MAPK1 | |
| SCHEMBL5452877 | 0.81 | AR (0.59) | L3MBTL1TDP1KDM4EALDH1A1MAPK1 | |
| SCHEMBL14967240 | 0.79 | L3MBTL1 (0.54) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL29659097 | 0.79 | L3MBTL1 (0.54) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL29409508 | 0.78 | KDM4E (0.40) | L3MBTL1TDP1KDM4EALDH1A1MAPK1 | |
| SCHEMBL1624009 | 0.78 | KDM4E (0.40) | L3MBTL1TDP1KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129409-A1 | Androgen receptor modulators | HU LAIN-YEN | 2007-06-07 | — | — | US | claimed |
| EP-1687274-A1 | ANDROGEN RECEPTOR MODULATORS | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | claimed |
| WO-2005049574-A1 | ANDROGEN RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | claimed |
| US-20070129409-A1 | Androgen receptor modulators | HU LAIN-YEN | 2007-06-07 | — | — | US | disclosed |
| EP-1687274-A1 | ANDROGEN RECEPTOR MODULATORS | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049574-A1 | ANDROGEN RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129409-A1 | Androgen receptor modulators | AR, FSHR, NR5A1 | L3MBTL1 4293/4885TDP1 3390/4885KDM4E 513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.