SCHEMBL5459240

SCHEMBL5459240

[CH2]c1cccc(CCCC)c1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.49
LIPG Q9Y5X9 3/20 0.49
SKP2 Q13309 1/20 0.44
NPC1 O15118 1/20 0.44
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
XIAP P98170 1/20 0.42
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
DRD2 P14416 1/20 0.39
OPRM1 P35372 1/20 0.39
DRD3 P35462 1/20 0.39
OPRD1 P41143 1/20 0.39
OPRK1 P41145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5252629 0.94 LPL (0.56) LPLLIPGPPARGPPARATDP1
Magnesium Chloride Anhydrous SCHEMBL29043242 0.93 LPL (0.44) LPLLIPGSKP2NPC1HPGD
SCHEMBL7331955 0.92 LPL (0.57) LPLLIPGPPARGPPARATDP1
SCHEMBL9064256 0.92 LPL (0.57) LPLLIPGPPARGPPARATDP1
SCHEMBL11650281 0.92 LPL (0.57) LPLLIPGPPARGPPARATDP1
SCHEMBL7332490 0.92 LPL (0.57) LPLLIPGPPARGPPARATDP1
SCHEMBL9063297 0.92 LPL (0.57) LPLLIPGPPARGPPARATDP1
SCHEMBL7337578 0.92 LPL (0.57) LPLLIPGPPARGPPARATDP1
SCHEMBL910501 0.87 CNR1 (0.42) LPLLIPGDRD2OPRM1DRD3
SCHEMBL347126 0.84 LPL (0.57) LPLLIPGSKP2NPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106588696-B A kind of preparation method of trans- 'alpha ', ' bela '-unsaturated nitrile class compound 西北师范大学 2018-12-25 CN claimed
CN-106588696-A Preparation method of trans-alpha, beta-unsaturated nitriles compound 西北师范大学 2017-04-26 CN claimed
US-6846953-B1 Aromatic amides WARNER LAMBERT COMPANY (US) 2005-01-25 US claimed
EP-1178953-B1 AROMATIC AMIDES WARNER LAMBERT CO (US) 2003-12-03 EP claimed
US-12012475-B2 Method of olefin polymerization using alkane-soluble non-metallocene precatalyst DOW GLOBAL TECHNOLOGIES LLC (US) 2024-06-18 US disclosed
CN-112823163-B Alkane soluble non-metallocene precatalyst 陶氏环球技术有限责任公司 2024-04-19 CN disclosed
US-11859031-B2 Alkane-soluble non-metallocene precatalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2024-01-02 US disclosed
EP-3877392-B1 ALKANE-SOLUBLE NON-METALLOCENE PRECATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-11-15 EP disclosed
CN-112839966-B Process for the polymerization of olefins using an alkane soluble non-metallocene pre-catalyst 陶氏环球技术有限责任公司 2023-07-28 CN disclosed
US-20220010045-A1 ALKANE-SOLUBLE NON-METALLOCENE PRECATALYSTS DOW GLOBAL TECHNOLOGIES LLC 2022-01-13 US disclosed
US-20210403615-A1 METHOD OF OLEFIN POLYMERIZATION USING ALKANE-SOLUBLE NON-METALLOCENE PRECATALYST DOW GLOBAL TECHNOLOGIES LLC 2021-12-30 US disclosed
EP-3877392-A1 ALKANE-SOLUBLE NON-METALLOCENE PRECATALYSTS Dow Global Technologies LLC (US) 2021-09-15 EP disclosed
US-4725601-A Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-02-16 US disclosed
CN-86104313-A The preparation method of Imidazoheterocyclic compounds 1987-03-04 CN disclosed
EP-0204285-A1 Imidazoheterocyclic compounds processes for preparation thereof and pharmaceutical compositions comprising them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-12-10 EP disclosed
US-4625009-A POLYMER OF N,N-DIMETHYLACRYLAMIDE, UNSATURATED CARBOXYLIC ACID, HYDROPHOBIC (METH)ACRYLATE ESTER, POLYALKYLENE GLYCOL DI(METH)ACRYLATE HOYA CORPORATION (JP) 1986-11-25 US disclosed
EP-0180897-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-14 EP disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed
US-4438277-A Hydronaphthalene derivatives SANKYO COMPANY, LIMITED (JP) 1984-03-20 US disclosed
US-4361515-A Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use SANKYO COMPANY, LIMITED (JP) 1982-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11859031-B2 Alkane-soluble non-metallocene precatalysts AP1M1, CCNA1, AMY1A LPL 2459/4885LIPG 4106/4885SKP2 154/4885
US-20220010045-A1 ALKANE-SOLUBLE NON-METALLOCENE PRECATALYSTS AP1M1, CCNA1, AMY1A LPL 2459/4885LIPG 4106/4885SKP2 154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.