Phosphoric Acid

Phosphoric Acid

SCHEMBL5459504

CC(N)(O)Cc1ccccc1.O=P(O)(O)O.O=P(O)(O)O

nearest known ligand 0.58

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.58
SLC6A2 P23975 1/20 0.55
TAAR1 Q96RJ0 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.50
HIF1A Q16665 1/20 0.50
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
LAP3 P28838 3/20 0.43
ANPEP P15144 1/20 0.43
GGPS1 O95749 2/20 0.42
LMNA P02545 1/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 2/20 0.42
TRPA1 O75762 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1698269 0.90 SLC6A2 (0.67) FDPSSLC6A2TAAR1SMN1; SMN2HIF1A
Pyrophosphoric Acid SCHEMBL5459506 0.90 FDPS (0.51) FDPSSLC6A2TAAR1SMN1; SMN2HIF1A
Sulfuric Acid SCHEMBL5465234 0.85 SLC6A2 (0.55) FDPSSLC6A2TAAR1SMN1; SMN2HIF1A
Isopropyl Alcohol SCHEMBL9580322 0.82 SLC6A2 (0.57) FDPSSLC6A2TAAR1SMN1; SMN2HIF1A
SCHEMBL5465236 0.79 SLC6A2 (0.48) FDPSSLC6A2TAAR1SMN1; SMN2HIF1A
SCHEMBL3419952 0.78 FDPS (0.66) FDPSSLC6A2TAAR1SMN1; SMN2HIF1A
Phosphoric Acid SCHEMBL28185049 0.77 FDPS (0.53) FDPSSLC6A2TAAR1SMN1; SMN2HIF1A
SCHEMBL4093885 0.76 FDPS (0.62) FDPSSLC6A2TAAR1SMN1; SMN2HIF1A
Acetic Acid SCHEMBL28732415 0.76 SLC6A2 (0.53) FDPSSLC6A2TAAR1SMN1; SMN2HIF1A
Phosphoric Acid SCHEMBL28194038 0.76 FDPS (0.56) FDPSSLC6A2TAAR1SMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070210476-A1 Machinable Resin Molded Product, Material For Forming The Same, And Model Made Of The Same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2007-09-13 US disclosed
EP-1728832-A1 MOLDING OF RESIN FOR CUTTING OPERATION, MATERIAL FOR FORMATION THEREOF AND MODEL Sanyo Chemical Industries, Ltd. (JP) 2006-12-06 EP disclosed