Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14096460 | 0.93 | KMT2A (0.71) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL28880300 | 0.81 | TSHR (0.81) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL23009259 | 0.80 | ALDH1A1 (1.00) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL31454744 | 0.79 | MAPT (0.83) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL5050992 | 0.79 | TSHR (0.76) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL28880361 | 0.78 | KDM4E (1.00) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL30410560 | 0.77 | TSHR (0.72) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| Nifenazone SCHEMBL25945 | 0.76 | KMT2A (1.00) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| Nifenazone SCHEMBL29481949 | 0.76 | KMT2A (1.00) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| Nifenazone SCHEMBL25422359 | 0.76 | KMT2A (1.00) | KMT2AMEN1MAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |