Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457165 | 0.99 | ALDH1A1 (0.44) | ALDH1A1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL2662739 | 0.87 | HCRTR1 (0.42) | HCRTR1HCRTR2MEN1KMT2AKDM4E | |
| SCHEMBL5463734 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL2662538 | 0.84 | HTT (0.38) | HCRTR1HCRTR2MEN1KMT2AGAA | |
| SCHEMBL5457294 | 0.83 | KMT2A (0.36) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL2643558 | 0.82 | MEN1 (0.53) | ALDH1A1MEN1KMT2AKDM4EHKDC1 | |
| SCHEMBL5464640 | 0.81 | AHR (0.42) | ALDH1A1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL2666573 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL5461495 | 0.80 | HCRTR1 (0.45) | HCRTR1HCRTR2MEN1KMT2AKDM4E | |
| SCHEMBL5464658 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070117808-A1 | Substituted Cycloalkylpyrrolones As Allosteric Modulators Of Glucokinase | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117808-A1 | Substituted Cycloalkylpyrrolones As Allosteric Modulators Of Glucokinase | GCKR, GCK, GALK1 | ALDH1A1 2410/4885HCRTR1 4451/4885HCRTR2 4027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.