Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 13/20 | 0.61 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.59 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL5457786 | 1.00 | FDPS (0.61) | FDPSSMPD1GGPS1LPAR1LPAR3 | |
| SCHEMBL999922 | 0.89 | FDPS (0.48) | FDPSSMPD1GGPS1 | |
| Pyrophosphoric Acid SCHEMBL5459848 | 0.88 | SMPD1 (0.56) | FDPSSMPD1GGPS1LPAR1LPAR3 | |
| Phosphoric Acid SCHEMBL5466869 | 0.87 | FDPS (0.57) | FDPSSMPD1GGPS1 | |
| Phosphoric Acid SCHEMBL8911229 | 0.84 | FDPS (0.63) | FDPSSMPD1GGPS1LPAR1LPAR3 | |
| SCHEMBL5391830 | 0.84 | FDPS (0.52) | FDPSSMPD1GGPS1 | |
| SCHEMBL1271337 | 0.84 | FDPS (0.52) | FDPSSMPD1GGPS1 | |
| SCHEMBL14840328 | 0.83 | FDPS (0.48) | FDPSSMPD1GGPS1 | |
| Sulfuric Acid SCHEMBL5462582 | 0.83 | FDPS (0.45) | FDPSSMPD1GGPS1 | |
| SCHEMBL7011302 | 0.81 | FDPS (0.46) | FDPSSMPD1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070210476-A1 | Machinable Resin Molded Product, Material For Forming The Same, And Model Made Of The Same | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| EP-1728832-A1 | MOLDING OF RESIN FOR CUTTING OPERATION, MATERIAL FOR FORMATION THEREOF AND MODEL | Sanyo Chemical Industries, Ltd. (JP) | 2006-12-06 | — | — | EP | disclosed |