Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21617570 | 0.74 | MEN1 (0.55) | MEN1POLBKMT2ALMNAALDH1A1 | |
| SCHEMBL8745001 | 0.71 | MEN1 (0.36) | MEN1POLBKMT2ALMNAALDH1A1 | |
| SCHEMBL3135606 | 0.66 | — | — | |
| SCHEMBL8162834 | 0.65 | GRM2 (0.38) | MEN1POLBKMT2ALMNAALDH1A1 | |
| SCHEMBL14332620 | 0.65 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2NISCHNR1H4SLC22A2 | |
| SCHEMBL2870202 | 0.62 | — | — | |
| Biphenyl SCHEMBL28376025 | 0.61 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPK1MAPTHSD17B10 | |
| SCHEMBL353825 | 0.59 | PARP1 (0.40) | POLBLMNANISCH | |
| Biphenyl SCHEMBL653702 | 0.58 | ALDH1A1 (0.82) | LMNAALDH1A1SMN1; SMN2TSHRMAPK1 | |
| Biphenyl SCHEMBL4002609 | 0.57 | ALDH1A1 (1.00) | LMNAALDH1A1SMN1; SMN2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027060-A1 | 2-METHYL-4-PHENY1-1,3-DIOXOLANE | PICKENHAGEN WILHELM | 2007-02-01 | — | — | US | disclosed |