Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14781259 | 0.77 | CYP2A6 (0.41) | GRM2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6288867 | 0.74 | MAPT (0.41) | LMNASMN1; SMN2TSHRNISCHALDH1A1 | |
| SCHEMBL3287440 | 0.72 | GRM2 (0.36) | GRM2MEN1KMT2ALMNAPOLB | |
| Biphenyl SCHEMBL1950563 | 0.67 | ALDH1A1 (0.50) | GRM2MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL5460700 | 0.65 | MEN1 (0.36) | GRM2MEN1KMT2ALMNAPOLB | |
| SCHEMBL1682639 | 0.62 | — | — | |
| SCHEMBL9530592 | 0.62 | BRD4 (0.40) | MEN1KMT2APOLBSMN1; SMN2TSHR | |
| SCHEMBL11506718 | 0.61 | SMN1; SMN2 (0.45) | MEN1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL8525660 | 0.61 | — | — | |
| SCHEMBL12946706 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763627-A | Process for preparing cyclopropyl alkyl ketones and 4,5-dihydroalkyfurans | HUELS AKTIENGESELLSCHAFT (DE) | 1998-06-09 | — | — | US | claimed |
| EP-0820977-B1 | Process for the preparation of cyclopropylalkylketones and 4,5-dihydroalkylfurans | DEGUSSA (DE) | 2000-04-26 | — | — | EP | disclosed |
| US-5763627-A | Process for preparing cyclopropyl alkyl ketones and 4,5-dihydroalkyfurans | HUELS AKTIENGESELLSCHAFT (DE) | 1998-06-09 | — | — | US | disclosed |
| EP-0820977-A1 | Process for the preparation of cyclopropylalkylketones and 4,5-dihydroalkylfurans | HÜLS AKTIENGESELLSCHAFT (DE) | 1998-01-28 | — | — | EP | disclosed |
| EP-0725066-B1 | Process for the production of cyclopropylalkylketones and 4,5-dihydroalkylfuranes | HUELS CHEMISCHE WERKE AG (DE) | 1997-07-16 | — | — | EP | disclosed |
| US-5629455-A | Process for preparing cyclopropyl alkyl ketones and 4,5-dihydroalkylfurans | HUELS AKTIENGESELLSCHAFT (DE) | 1997-05-13 | — | — | US | disclosed |
| EP-0725066-A1 | Process for the production of cyclopropylalkylketones and 4,5-dihydroalkylfuranes | HÜLS AKTIENGESELLSCHAFT (DE) | 1996-08-07 | — | — | EP | disclosed |