Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5466103 | 0.90 | NAMPT (0.59) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5465649 | 0.85 | KMT2A (0.60) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5460804 | 0.84 | MAPT (0.68) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5460938 | 0.84 | NAMPT (0.64) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13853617 | 0.83 | NAMPT (0.66) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5470937 | 0.83 | MAPT (0.53) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5466754 | 0.83 | NAMPT (0.61) | NAMPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7332428 | 0.82 | NAMPT (0.65) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5466981 | 0.82 | NAMPT (0.59) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5466989 | 0.82 | NAMPT (0.59) | NAMPTMAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | NAMPT 324/4885MAPT 758/4885SMN1; SMN2 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.