Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | UBE2N | P61088 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.49 |
| ▸ | FLT1 | P17948 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449295 | 0.87 | ALDH1A1 (0.64) | KMT2AUBE2NKDRKDM4EHSD17B10 | |
| SCHEMBL5453309 | 0.77 | PTPN1 (0.46) | KMT2AKDM4EHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL5467867 | 0.75 | MAPK14 (0.53) | KDRPDGFRBFLT1 | |
| SCHEMBL31208326 | 0.72 | ALDH1A1 (0.47) | KMT2AUBE2NKDRKDM4EHSD17B10 | |
| SCHEMBL5463075 | 0.72 | FLT3 (0.53) | KMT2AKDM4EALDH1A1MAPTGAA | |
| Hydrochloric Acid SCHEMBL31208318 | 0.71 | ALDH1A1 (0.47) | KMT2AUBE2NKDRKDM4EHSD17B10 | |
| SCHEMBL5455772 | 0.71 | CFTR (0.54) | KMT2AUBE2NKDRKDM4EHSD17B10 | |
| SCHEMBL5450990 | 0.70 | PTPN1 (0.51) | KMT2AKDM4EHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL5458457 | 0.70 | FLT3 (0.52) | KMT2AMAPTMEN1 | |
| SCHEMBL5451512 | 0.69 | FLT3 (0.49) | KMT2AKDM4EALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | KMT2A 4785/4885UBE2N 4748/4885KDR 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.