SCHEMBL546221

SCHEMBL546221

Cc1cccc2sc(SNC(C)(C)C)nc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
MAPT P10636 7/20 0.43
PKM P14618 1/20 0.41
GAA P10253 1/20 0.40
ACHE P22303 1/20 0.39
GRIN2B Q13224 1/20 0.39
MEN1 O00255 8/20 0.38
KMT2A Q03164 8/20 0.38
KDM4E B2RXH2 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ATM Q13315 1/20 0.38
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
RAB9A P51151 1/20 0.38
LMNA P02545 4/20 0.38
ALOX15 P16050 2/20 0.38
POLB P06746 2/20 0.38
HPGD P15428 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8509631 0.86 ALDH1A1 (0.44) ALDH1A1MAPTPKMGAAACHE
SCHEMBL8513075 0.85 ALDH1A1 (0.43) ALDH1A1MAPTPKMGAAACHE
SCHEMBL7074954 0.84 ALDH1A1 (0.33) ALDH1A1MAPTPKMGAAMEN1
SCHEMBL8532908 0.83 ALDH1A1 (0.41) ALDH1A1MAPTPKMGAAACHE
SCHEMBL8512794 0.83 ALDH1A1 (0.41) ALDH1A1MAPTPKMGAAACHE
SCHEMBL7519962 0.81 MAPT (0.34) ALDH1A1MAPTPKMGAAMEN1
SCHEMBL6689383 0.81 ALDH1A1 (0.52) ALDH1A1MAPTGAAMEN1KMT2A
SCHEMBL6690619 0.81 MEN1 (0.45) ALDH1A1MAPTPKMGAAMEN1
SCHEMBL24602984 0.80 ALDH1A1 (0.53) ALDH1A1MAPTPKMGAAACHE
SCHEMBL6694175 0.79 MEN1 (0.36) ALDH1A1MAPTPKMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110634-B2 Sulfenamide accelerators for improved network stabilization of rubber vulcanizates Nocil, Ltd (IN) 2012-02-07 US claimed
CN-117715967-A Rubber composition for hose inner pipe, laminate, and hose 株式会社普利司通 2024-03-15 CN disclosed
US-20210402381-A1 RUBBER COMPOSITIONS AND METHODS KREUTZ FERNANDO THOME (BR) 2021-12-30 US disclosed
US-8110634-B2 Sulfenamide accelerators for improved network stabilization of rubber vulcanizates Nocil, Ltd (IN) 2012-02-07 US disclosed
US-8110634-B2 Sulfenamide accelerators for improved network stabilization of rubber vulcanizates Nocil, Ltd (IN) 2012-02-07 US disclosed
US-20100234535-A1 NOVEL SULFENAMIDE ACCELERATORS FOR IMPROVED NETWORK STABILIZATION OF RUBBER VULCANIZATES NOCIL, LTD. (IN) 2010-09-16 US disclosed
US-20100234535-A1 NOVEL SULFENAMIDE ACCELERATORS FOR IMPROVED NETWORK STABILIZATION OF RUBBER VULCANIZATES NOCIL, LTD. (IN) 2010-09-16 US disclosed
WO-2010084506-A2 NOVEL SULFENAMIDE ACCELERATORS FOR REPLACEMENT OF CONVENTIONAL SULFENAMIDE ACCELERATOR DCBS (DICYCLOHEXYL BENZOTHIAZOLE SULFENAMIDE) IN STEEL CORD SKIM (WIRE COATING) COMPOUND NOCIL LIMITED (IN) 2010-07-29 WO disclosed
WO-2008035375-A2 NOVEL SULFENAMIDE ACCELERATORS FOR IMPROVED NETWORK STABILIZATION OF RUBBER VULCANIZATES NATIONAL ORGANIC CHEMICAL INDUSTRIES LIMITED (IN) 2008-03-27 WO disclosed
EP-0869016-B1 Pneumatic radial tires BRIDGESTONE CORP (JP) 2004-03-03 EP disclosed
US-6336486-B1 Pneumatic radical tire having cap base tread BRIDGESTONE CORPORATION (JP) 2002-01-08 US disclosed
EP-0869016-A2 Pneumatic radial tires Bridgestone Corporation (JP) 1998-10-07 EP disclosed