SCHEMBL6690619

SCHEMBL6690619

CCc1cccc2sc(SNC(C)(C)C)nc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
IDO1 P14902 1/20 0.40
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 5/20 0.38
LMNA P02545 6/20 0.37
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
HTT P42858 2/20 0.37
RECQL P46063 1/20 0.37
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 2/20 0.33
ATM Q13315 1/20 0.33
GAA P10253 3/20 0.33
FBP1 P09467 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
SLC2A1 P11166 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29683632 0.89 MEN1 (0.36) MEN1KMT2AIDO1MAPTSMN1; SMN2
SCHEMBL6694175 0.89 MEN1 (0.36) MEN1KMT2AIDO1MAPTSMN1; SMN2
SCHEMBL546221 0.81 ALDH1A1 (0.49) MEN1KMT2AMAPTSMN1; SMN2LMNA
SCHEMBL1771423 0.81 MEN1 (0.49) MEN1KMT2AIDO1MAPTSMN1; SMN2
SCHEMBL6693674 0.80 ALDH1A1 (0.56) MEN1KMT2AMAPTSMN1; SMN2LMNA
SCHEMBL7074954 0.80 ALDH1A1 (0.33) MEN1KMT2AMAPTSMN1; SMN2LMNA
SCHEMBL27560295 0.79 MEN1 (0.48) MEN1KMT2AIDO1MAPTSMN1; SMN2
SCHEMBL30114670 0.79 SMN1; SMN2 (0.35) MEN1KMT2AIDO1SMN1; SMN2LMNA
SCHEMBL6689073 0.78 KMT2A (0.44) MEN1KMT2AMAPTLMNAHTT
SCHEMBL11771432 0.78 MEN1 (0.50) MEN1KMT2AIDO1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106133047-B Rubber composition for tire, pneumatic tire, and method for producing rubber composition for tire 住友橡胶工业株式会社 2019-05-07 CN disclosed
CN-104558796-A High-temperature-resistant food-grade preservative film CHANGZHOU NUORUIGE NANO TECHNOLOGY CO LTD 2015-04-29 CN disclosed
EP-0869016-B1 Pneumatic radial tires BRIDGESTONE CORP (JP) 2004-03-03 EP disclosed
US-6336486-B1 Pneumatic radical tire having cap base tread BRIDGESTONE CORPORATION (JP) 2002-01-08 US disclosed
EP-0869016-A2 Pneumatic radial tires Bridgestone Corporation (JP) 1998-10-07 EP disclosed