SCHEMBL54635

SCHEMBL54635

S=c1sc2nc3ccccc3nc2s1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.48
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 3/20 0.46
KDM4E B2RXH2 3/20 0.46
HPGD P15428 3/20 0.46
GAA P10253 1/20 0.46
TDP1 Q9NUW8 3/20 0.40
NQO2 P16083 3/20 0.39
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ADRA2A P08913 1/20 0.35
FBP1 P09467 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
DRD2 P14416 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30061114 1.00 MAPT (0.48) MAPTALDH1A1HSD17B10KDM4EHPGD
Hydrochlorthiazide SCHEMBL4422849 0.82 KDM4E (0.32) MAPTALDH1A1HSD17B10KDM4EHPGD
SCHEMBL6652225 0.78 ALDH1A1 (0.45) MAPTALDH1A1HSD17B10KDM4EHPGD
Chinomethionat SCHEMBL1069085 0.77 TDP1 (0.77) MAPTALDH1A1KDM4EHPGDTDP1
SCHEMBL556965 0.75 TDP1 (0.59) MAPTALDH1A1HSD17B10KDM4EHPGD
SCHEMBL10921480 0.71 MEN1 (0.58) MAPTALDH1A1KDM4EHPGDTDP1
Phenazine SCHEMBL27643128 0.67 MAPT (1.00) MAPTALDH1A1HSD17B10KDM4EHPGD
Phenazine SCHEMBL9049 0.67 MAPT (1.00) MAPTALDH1A1HSD17B10KDM4EHPGD
Phenazine SCHEMBL29356959 0.67 MAPT (1.00) MAPTALDH1A1HSD17B10KDM4EHPGD
SCHEMBL11807766 0.67 MAPT (0.39) MAPTALDH1A1HSD17B10KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5937 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
US-12471599-B2 Agricultural compositions comprising remodeled nitrogen fixing microbes PIVOT BIO, INC. (US) 2025-11-18 US claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-4627920-A1 BINARY INSECTICIDE COMPOSITION AND USE THEREOF Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) 2025-10-08 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
US-20250185667-A1 AGRICULTURAL COMPOSITIONS COMPRISING REMODELED NITROGEN FIXING MICROBES HSBC BANK USA, N.A. 2025-06-12 US claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
US-20250143298-A1 PEST MANAGEMENT BIO-GENE TECHNOLOGY LIMITED (AU) 2025-05-08 US claimed
US-20250017207-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-01-16 US claimed
WO-2006015865-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-02-16 WO claimed
CN-1473468-A Plumbagin miticide and its preparing method 华南农业大学 2004-02-11 CN claimed
US-6436421-B1 Pesticide compositions ?ROHM AND HAAS COMPANY 2002-08-20 US claimed
WO-2000062792-A2 COMPOSITIONS AND METHODS FOR CONTROLLING PESTS INSECT BIOTECHNOLOGY, INC. (US) 2000-10-26 WO claimed
US-5730996-A Intercalates and expoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1998-03-24 US claimed
CN-86105439-A Plant protection composition 1988-03-09 CN claimed
EP-0085907-B1 QUINOXALINE COMPOUNDS OR A COMBINATION THEREOF WITH O-DICHLOROBENZENE FOR USE AGAINST ANIMAL COCCIDIOSIS Eisai Co., Ltd. (JP) 1986-08-20 EP claimed
EP-0068294-B1 A NEW ACARICIDAL COMPOSITION, PROCESSES FOR ITS PRODUCTION AND ITS USE A. Nattermann & Cie. GmbH (DE) 1985-12-18 EP claimed
EP-0085907-A1 Quinoxaline compounds or a combination thereof with o-dichlorobenzene for use against animal coccidiosis Eisai Co., Ltd. (JP) 1983-08-17 EP claimed
EP-0068294-A1 A new acaricidal composition, processes for its production and its use A. Nattermann & Cie. GmbH (DE) 1983-01-05 EP claimed