Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472804 | 0.84 | TDP1 (0.58) | TDP1MAPTALDH1A1KDM4EHPGD | |
| Chinomethionat SCHEMBL1069085 | 0.77 | TDP1 (0.77) | TDP1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL10923431 | 0.76 | TDP1 (0.50) | TDP1MAPTALDH1A1HSD17B10RAB9A | |
| SCHEMBL30061114 | 0.75 | MAPT (0.48) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL54635 | 0.75 | MAPT (0.48) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| Chinomethionat SCHEMBL29358969 | 0.74 | TDP1 (1.00) | TDP1MAPTALDH1A1KDM4ESMN1; SMN2 | |
| Phenazine SCHEMBL9049 | 0.67 | MAPT (1.00) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| Phenazine SCHEMBL29356959 | 0.67 | MAPT (1.00) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| Phenazine SCHEMBL27643128 | 0.67 | MAPT (1.00) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL11807766 | 0.67 | MAPT (0.39) | TDP1MAPTALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085907-B1 | QUINOXALINE COMPOUNDS OR A COMBINATION THEREOF WITH O-DICHLOROBENZENE FOR USE AGAINST ANIMAL COCCIDIOSIS | Eisai Co., Ltd. (JP) | 1986-08-20 | — | — | EP | claimed |
| EP-0085907-A1 | Quinoxaline compounds or a combination thereof with o-dichlorobenzene for use against animal coccidiosis | Eisai Co., Ltd. (JP) | 1983-08-17 | — | — | EP | claimed |
| US-8530673-B2 | Tetrathiafulvalene derivative, and organic film and organic transistor using the same | RICOH COMPANY, LTD. (JP) | 2013-09-10 | — | — | US | disclosed |
| US-20120035364-A1 | TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME | RICOH COMPANY, LTD. (JP) | 2012-02-09 | — | — | US | disclosed |
| EP-0085907-B1 | QUINOXALINE COMPOUNDS OR A COMBINATION THEREOF WITH O-DICHLOROBENZENE FOR USE AGAINST ANIMAL COCCIDIOSIS | Eisai Co., Ltd. (JP) | 1986-08-20 | — | — | EP | disclosed |
| US-4434166-A | 1,3-DITHIOLO(4,5-B)QUINOXALINE DERIVATIVES | EISAI CO., LTD. (JP) | 1984-02-28 | — | — | US | disclosed |
| EP-0085907-A1 | Quinoxaline compounds or a combination thereof with o-dichlorobenzene for use against animal coccidiosis | Eisai Co., Ltd. (JP) | 1983-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035364-A1 | TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME | TCOF1, F12, F5 | TDP1 711/4885MAPT 1984/4885ALDH1A1 2811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.