Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27190337 | 0.75 | MEN1 (0.61) | MEN1BLMKMT2A | |
| SCHEMBL5746785 | 0.75 | MEN1 (0.61) | MEN1BLMKMT2A | |
| SCHEMBL9511045 | 0.75 | MEN1 (0.61) | MEN1BLMKMT2A | |
| SCHEMBL10344448 | 0.74 | MAPK1 (0.39) | KMT2A | |
| SCHEMBL11931404 | 0.74 | MEN1 (0.42) | MEN1BLMKMT2A | |
| SCHEMBL17756096 | 0.69 | MEN1 (0.61) | MEN1BLMKMT2A | |
| SCHEMBL2177343 | 0.69 | MEN1 (0.61) | MEN1BLMKMT2A | |
| SCHEMBL5257403 | 0.68 | HSD17B10 (0.50) | MEN1KMT2A | |
| SCHEMBL5256483 | 0.68 | HSD17B10 (0.50) | MEN1KMT2A | |
| SCHEMBL5258129 | 0.66 | HPGD (0.51) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | MEN1 3032/4885BLM 4054/4885KMT2A 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.