SCHEMBL546444

SCHEMBL546444

C1CCC(OCCOC2CCCC2)C1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.56
HPGD P15428 1/20 0.34
NAAA Q02083 1/20 0.33
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA12 O43570 2/20 0.32
CA9 Q16790 2/20 0.32
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6376493 0.97 NPC1 (0.61) NPC1HPGDNAAACA1CA2
SCHEMBL6383859 0.97 NPC1 (0.61) NPC1HPGDNAAACA1CA2
SCHEMBL27888489 0.97 NPC1 (0.54) NPC1HPGDNAAACA1CA2
SCHEMBL6377426 0.97 NPC1 (0.61) NPC1HPGDNAAACA1CA2
SCHEMBL10357183 0.97 NPC1 (0.61) NPC1HPGDNAAACA1CA2
SCHEMBL6379525 0.97 NPC1 (0.61) NPC1HPGDNAAACA1CA2
SCHEMBL6382583 0.93 NPC1 (0.50) NPC1HPGD
SCHEMBL27888448 0.88 NPC1 (0.48) NPC1HPGD
SCHEMBL13734694 0.86 NPC1 (0.46) NPC1HPGD
SCHEMBL14359727 0.86 NPC1 (0.46) NPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325456-A1 POLYMER COMPOUNDS AND APPLICATION THEREOF SAMYANG CORPORATION (KR) 2025-10-23 US claimed
EP-4626495-A1 OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF Johnson & Johnson Surgical Vision, Inc. (US) 2025-10-08 EP claimed
CN-119662188-A UV adhesive for packaging GOB of LED display screen, and preparation method and application thereof 河源然生新材料有限公司 2025-03-21 CN claimed
CN-119613610-A Intraocular lens material and preparation method thereof 微创视神医疗科技(上海)有限公司 2025-03-14 CN claimed
EP-4455175-A1 POLYMER COMPOUND AND APPLICATION THEREOF Samyang Corporation (KR) 2024-10-30 EP claimed
US-12071497-B2 High refractive index, high Abbe compositions Johnson & Johnson Surgical Vision, Inc. (US) 2024-08-27 US claimed
US-20240209129-A1 OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF Johnson & Johnson Surgical Vision, Inc. 2024-06-27 US claimed
WO-2024116106-A1 OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF Johnson & Johnson Surgical Vision, Inc. (US) 2024-06-06 WO claimed
US-11795252-B2 Compositions with high refractive index and Abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2023-10-24 US claimed
US-20230279169-A1 HIGH REFRACTIVE INDEX, HIGH ABBE COMPOSITIONS Johnson & Johnson Surgical Vision, Inc. 2023-09-07 US claimed
EP-2586027-A1 LOW VISCOSITY MONOMER FOR PATTERNING OPTICAL TAPE Oracle International Corporation (US) 2013-05-01 EP claimed
US-8399102-B2 Moisture-hardening compositions containing silane-functional polymers and aminosilane adducts SIKA TECHNOLOGY AG (CH) 2013-03-19 US claimed
WO-2013023545-A1 OPTICAL TRANSPARENT DUAL CURE ADHESIVES COMPOSITION HENKEL (CHINA) COMPANY LIMITED (CN) 2013-02-21 WO claimed
US-8110305-B2 Rechargeable lithium battery SAMSUNG SDI CO., LTD. (KR) 2012-02-07 US claimed
WO-2011163543-A1 LOW VISCOSITY MONOMER FOR PATTERNING OPTICAL TAPE ORACLE INTERNATIONAL CORPORATION (US) 2011-12-29 WO claimed
US-20110318534-A1 Low Viscosity Monomer for Patterning Optical Tape ORACLE INTERNATIONAL CORPORATION (US) 2011-12-29 US claimed
US-20100159254-A1 Moisture-Hardening Compositions Containing Silane-Functional Polymers and Aminosilane Adducts SIKA TECHNOLOGY AG (CH) 2010-06-24 US claimed
EP-2013305-B1 MOISTURE-HARDENING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS AND AMINOSILANE ADDUCTS SIKA TECHNOLOGY AG (CH) 2009-10-14 EP claimed
WO-2005047407-A1 UV CURABLE COMPOSITION FOR FORMING DIELECTRIC COATINGS AND RELATED METHOD ALLIED PHOTOCHEMICAL, INC. (US) 2005-05-26 WO claimed
US-20050101685-A1 UV curable composition for forming dielectric coatings and related method ALLIED PHOTOCHEMICAL, INC. (US) 2005-05-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325456-A1 POLYMER COMPOUNDS AND APPLICATION THEREOF ILK, PNN, EPCAM NPC1 469/4885HPGD 1424/4885NAAA 2013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.