Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20271932 | 0.84 | MEN1 (0.36) | DHODHSPRALDH1A1SMN1; SMN2CHEK1 | |
| Hydrochloric Acid SCHEMBL27786826 | 0.82 | MEN1 (0.35) | DHODHALDH1A1SMN1; SMN2CHEK1AURKA | |
| Hydrochloric Acid SCHEMBL27786824 | 0.81 | MEN1 (0.34) | DHODHALDH1A1SMN1; SMN2CHEK1AURKA | |
| SCHEMBL27403027 | 0.76 | CA12 (0.36) | ALDH1A1KDM4ESMN1; SMN2MAPK8CYP1A2 | |
| SCHEMBL359924 | 0.73 | GPR35 (0.37) | SPRDAOALDH1A1KMOKDM4E | |
| SCHEMBL5463111 | 0.72 | NTRK1 (0.33) | CHEK1AURKADAPK3JAK2ABL1 | |
| SCHEMBL27404715 | 0.72 | MMP9 (0.37) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1694162 | 0.72 | HPGD (0.49) | ALDH1A1GAAKDM4ESMN1; SMN2MAPK8 | |
| SCHEMBL11847845 | 0.71 | KDM4E (0.40) | ALDH1A1GAAKDM4E | |
| SCHEMBL26042354 | 0.70 | DHODH (0.44) | DHODHSPRPKMALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101198614-B | Thienopyrimidine derivative | ASKA PHARM CO LTD | 2011-07-06 | — | — | CN | disclosed |
| CN-101198614-A | Thienopyrimidine derivative | ASKA PHARM CO LTD (JP) | 2008-06-11 | — | — | CN | disclosed |
| CN-1976907-A | Heterocyclic amide compound and use thereof as an MMP-13 inhibitor | TAKEDA PHARMACEUTICAL (JP) | 2007-06-06 | — | — | CN | disclosed |
| US-20070010402-A1 | Novel herbicides, usage thereof, novel thienopyrimidine derivatives, intermediates of the same, and process for production thereof | NIHON NOHYAKU CO., LTD., (JP) | 2007-01-11 | — | — | US | disclosed |
| EP-1544202-A1 | NOVEL HERBICIDES, USAGE THEREOF, NOVEL THIENOPYRIMIDINE DERIVATIVES, INTERMEDIATES OF THE SAME, AND PROCESS FOR PRODUCTION THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2005-06-22 | — | — | EP | disclosed |
| CN-1346358-A | Thienopyrimidine compounds and salts thereof and process for producing the same | NIPPON SODA CO (JP) | 2002-04-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010402-A1 | Novel herbicides, usage thereof, novel thienopyrimidine derivatives, intermediates of the same, and process for production thereof | DDT, DPYD, DHODH | DHODH 3/4885SPR 749/4885DAO 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.