Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.78 |
| ▸ | CA2 | P00918 | 4/20 | 0.78 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.78 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.78 |
| ▸ | PARP1 | P09874 | 1/20 | 0.78 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201761 | 0.88 | PARP10 (1.00) | CA1CA2PARP10PARP4PARP1 | |
| Hydrochloric Acid SCHEMBL408766 | 0.86 | PARP10 (0.95) | CA1CA2PARP10PARP4PARP1 | |
| Hydrochloric Acid SCHEMBL4376056 | 0.86 | PARP10 (0.95) | CA1CA2PARP10PARP4PARP1 | |
| SCHEMBL11895727 | 0.86 | RAB9A (0.76) | CA1CA2PARP10PARP4PARP1 | |
| SCHEMBL4645978 | 0.84 | PARP1 (0.61) | CA1CA2PARP10PARP4PARP1 | |
| SCHEMBL5436969 | 0.83 | CA1 (0.81) | CA1CA2NPC1MAPTRAB9A | |
| SCHEMBL5442673 | 0.83 | CA1 (0.77) | CA1CA2NPC1MAPTRAB9A | |
| SCHEMBL5460493 | 0.83 | MAPT (0.65) | CA1CA2PARP10PARP4PARP1 | |
| SCHEMBL7442028 | 0.82 | PARP10 (0.88) | CA1CA2PARP10PARP4PARP1 | |
| Acetic Acid SCHEMBL28396208 | 0.82 | PARP10 (0.88) | CA1CA2PARP10PARP4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129433-A1 | Diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2007-06-07 | — | — | US | claimed |
| EP-1687253-A2 | DIPHENYLAMINE DERIVATIVES | Merk Patent Gmbh (DE) | 2006-08-09 | — | — | EP | claimed |
| WO-2005051888-A2 | DIPHENYLAMINE DERIVATIVES | MERK PATENT GMBH (DE) | 2005-06-09 | — | — | WO | claimed |
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | AJINOMOTO CO. INC | 2004-01-01 | — | — | US | claimed |
| CN-107325019-B | Aryl amine benzamide compound and N- aryl-aryl amine benzamide compound preparation method | 石河子大学 | 2019-11-22 | — | — | CN | disclosed |
| CN-107325019-A | The preparation method of aryl amine benzamide compound and N aryl aryl amine benzamide compounds | 石河子大学 | 2017-11-07 | — | — | CN | disclosed |
| US-20070129433-A1 | Diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
| US-20070129433-A1 | Diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | AJINOMOTO CO. INC | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | NOS3, CBR3, CBR1 | CA1 2615/4885CA2 1737/4885PARP10 1967/4885 |
| US-20070129433-A1 | Diphenylamine derivatives | CCNY, CHKB, CHKA | CA1 1145/4885CA2 346/4885PARP10 1284/4885 |
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | NFKBIA, IKBKB, CHUK | CA1 679/4885CA2 680/4885PARP10 2792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.