Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456115 | 1.00 | MT-CO2 (0.38) | MT-CO2POLBPIM1SLC18A3MAPT | |
| SCHEMBL5458664 | 1.00 | MT-CO2 (0.38) | MT-CO2POLBPIM1SLC18A3MAPT | |
| SCHEMBL5456112 | 1.00 | MT-CO2 (0.38) | MT-CO2POLBPIM1SLC18A3MAPT | |
| SCHEMBL5456121 | 1.00 | MT-CO2 (0.38) | MT-CO2POLBPIM1SLC18A3MAPT | |
| SCHEMBL9340804 | 0.77 | NPSR1 (0.53) | MT-CO2POLBMAPTRAB9AGAA | |
| SCHEMBL9341420 | 0.77 | MT-CO2 (0.41) | MT-CO2POLBMAPTRAB9AGAA | |
| SCHEMBL9341425 | 0.77 | MT-CO2 (0.41) | MT-CO2POLBMAPTRAB9AGAA | |
| SCHEMBL9341423 | 0.77 | MT-CO2 (0.41) | MT-CO2POLBMAPTRAB9AGAA | |
| SCHEMBL12820989 | 0.75 | NPSR1 (0.64) | POLBGAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5592334 | 0.75 | ALDH1A1 (0.41) | MT-CO2POLBPIM1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197797-A1 | Compounds and methods for carbazole synthesis | ROCHE COLORADO CORPORATION | 2007-08-23 | — | — | US | disclosed |
| WO-2007077111-A1 | COMPOUNDS AND METHODS FOR CARBAZOLE SYNTHESIS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197797-A1 | Compounds and methods for carbazole synthesis | CNR2, CNR1, CYP2J2 | MT-CO2 730/4885POLB 3319/4885PIM1 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.