SCHEMBL5465707

SCHEMBL5465707

CCCC(O)OC(C)OCC

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
TSHR P16473 2/20 0.35
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6022000 0.85 LMNA (0.42) LMNA
SCHEMBL5466586 0.81 TSHR (0.38) LMNATSHR
SCHEMBL1769965 0.81 TSHR (0.57) LMNATSHRTHRB
SCHEMBL9127516 0.81 SPHK1 (0.31) TSHR
SCHEMBL6046423 0.81 LMNA (0.42) LMNATSHR
SCHEMBL28091393 0.79 LMNA (0.50) LMNATSHRTHRB
SCHEMBL12518006 0.78
SCHEMBL107911 0.78
SCHEMBL7635050 0.77 TSHR (0.35) LMNATSHRTHRB
SCHEMBL4936840 0.77 LMNA (0.48) LMNATSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8834934-B2 Material encapsulation system HAVILAND PRODUCTS COMPANY (US) 2014-09-16 US claimed
US-20060110464-A1 Material encapsulation system HAVILAND PRODUCTS COMPANY 2006-05-25 US claimed
EP-1596831-A2 MATERIAL INCAPSULATION SYSTEM Venture Management Alliance, LLC (US) 2005-11-23 EP claimed
WO-2004073033-A2 MATERIAL INCAPSULATION SYSTEM VENTURE MANAGEMENT ALLIANCE, LLC (US) 2004-08-26 WO claimed
US-20140364352-A1 Material Release System HAVILAND PRODUCTS COMPANY (US) 2014-12-11 US disclosed
US-8834934-B2 Material encapsulation system HAVILAND PRODUCTS COMPANY (US) 2014-09-16 US disclosed
US-20070112141-A1 Rubber composition, vulcanizable rubber composition, and vulcanizate ZEON CORPORATION (JP) 2007-05-17 US disclosed
US-20060281865-A1 Polymer alloy, crosslinked object, and fuel hose ZEON CORPORATION (JP) 2006-12-14 US disclosed
US-20060110464-A1 Material encapsulation system HAVILAND PRODUCTS COMPANY 2006-05-25 US disclosed
EP-1640413-A2 POLYMER ALLOY, CROSSLINKED OBJECT, AND FUEL HOSE ZEON CORPORATION (JP) 2006-03-29 EP disclosed
EP-1596831-A2 MATERIAL INCAPSULATION SYSTEM Venture Management Alliance, LLC (US) 2005-11-23 EP disclosed
US-20050245683-A1 Polymer alloy, crosslinked articles, and fuel hoses ZEON CORPORATION (JP) 2005-11-03 US disclosed
EP-1548056-A1 POLYMER ALLOY, CROSSLINKED ARTICLES, AND FUEL HOSES Zeon Corporation (JP) 2005-06-29 EP disclosed
WO-2004073033-A2 MATERIAL INCAPSULATION SYSTEM VENTURE MANAGEMENT ALLIANCE, LLC (US) 2004-08-26 WO disclosed
EP-1152029-A1 POLYBLEND COMPOSITION, CROSSLINKED OBJECT, AND HOSE FOR FUEL NIPPON ZEON CO., LTD. (JP) 2001-11-07 EP disclosed
US-5631308-A SELF-POLISHING METALLIZED COPOLYMER KOREA CHEMICAL CO., LTD. (KR) 1997-05-20 US disclosed