Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL546579

C=CCOC(C(=O)O)C(OCC=C)C(=O)O.N

nearest known ligand 0.40

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.32
GRIK2 Q13002 2/20 0.32
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SLC1A3 P43003 5/20 0.31
SLC1A2 P43004 5/20 0.31
SLC1A1 P43005 5/20 0.31
CYP2C19 P33261 1/20 0.31
CPA1 P15085 1/20 0.31
TSHR P16473 1/20 0.31
MAPT P10636 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6394261 0.98 GRIK1 (0.33) GRIK1GRIK2CYP3A4TDP1SLC1A3
SCHEMBL7418039 0.85 TSHR (0.36) TSHRCA1CA2CA7
SCHEMBL5697726 0.83 TDP1 (0.35) TDP1TSHRCA1CA2CA7
Ammonia Solution, Strong SCHEMBL9302589 0.81 GRIK1 (0.32) GRIK1GRIK2CYP3A4TDP1CYP2C19
SCHEMBL4563384 0.78 FNTA (0.43) GRIK1GRIK2CYP3A4TDP1CYP2C19
SCHEMBL541955 0.78 GRIK1 (0.33) GRIK1GRIK2CYP3A4TDP1CYP2C19
SCHEMBL9302677 0.76 GRIK1 (0.32) GRIK1GRIK2CYP3A4TDP1CYP2C19
SCHEMBL5163974 0.76 GRIK1 (0.32) GRIK1GRIK2CYP3A4TDP1CYP2C19
SCHEMBL7197484 0.76
SCHEMBL6394457 0.76 MAPT (0.38) CYP3A4TDP1TSHRMAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8776367-B2 Method of manufacturing an electret film NATIONAL TAIWAN UNIVERSITY (TW) 2014-07-15 US claimed
US-8111847-B2 Electret materials, electret speakers, and methods of manufacturing the same NATIONAL TAIWAN UNIVERSITY (TW) 2012-02-07 US claimed
US-20090245547-A1 ELECTRET MATERIALS, ELECTRET SPEAKERS, AND METHODS OF MANUFACTURING THE SAME NATIONAL TAIWAN UNIVERSITY 2009-10-01 US claimed
US-20090169036-A1 ELECTRET MATERIALS, ELECTRET SPEAKERS, AND METHODS OF MANUFACTURING THE SAME NATIONAL TAIWAN UNIVERSITY 2009-07-02 US claimed
US-8776367-B2 Method of manufacturing an electret film NATIONAL TAIWAN UNIVERSITY (TW) 2014-07-15 US disclosed
US-8111847-B2 Electret materials, electret speakers, and methods of manufacturing the same NATIONAL TAIWAN UNIVERSITY (TW) 2012-02-07 US disclosed
US-20090245547-A1 ELECTRET MATERIALS, ELECTRET SPEAKERS, AND METHODS OF MANUFACTURING THE SAME NATIONAL TAIWAN UNIVERSITY 2009-10-01 US disclosed
US-20090169036-A1 ELECTRET MATERIALS, ELECTRET SPEAKERS, AND METHODS OF MANUFACTURING THE SAME NATIONAL TAIWAN UNIVERSITY 2009-07-02 US disclosed
US-20050014830-A1 Substances for breaking down conformation of microbes NATIONAL TAIWAN UNIVERSITY (TW) 2005-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014830-A1 Substances for breaking down conformation of microbes CD14, FABP2, MIF GRIK1 2314/4885GRIK2 2260/4885CYP3A4 3025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.