SCHEMBL6394261

SCHEMBL6394261

C=CCOC(C(=O)O)C(OCC=C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.33
GRIK2 Q13002 2/20 0.33
CYP3A4 P08684 1/20 0.33
SLC1A3 P43003 5/20 0.32
SLC1A2 P43004 5/20 0.32
SLC1A1 P43005 5/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP2C19 P33261 1/20 0.32
CPA1 P15085 1/20 0.32
TSHR P16473 1/20 0.31
MAPT P10636 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL546579 0.98 GRIK1 (0.32) GRIK1GRIK2CYP3A4SLC1A3SLC1A2
SCHEMBL7418039 0.87 TSHR (0.36) TSHRCA1CA2CA7
SCHEMBL5697726 0.85 TDP1 (0.35) TDP1TSHRCA1CA2CA7
SCHEMBL4563384 0.80 FNTA (0.43) GRIK1GRIK2CYP3A4TDP1CYP2C19
SCHEMBL541955 0.80 GRIK1 (0.33) GRIK1GRIK2CYP3A4TDP1CYP2C19
SCHEMBL9302677 0.78 GRIK1 (0.32) GRIK1GRIK2CYP3A4TDP1CYP2C19
SCHEMBL5163974 0.78 GRIK1 (0.32) GRIK1GRIK2CYP3A4TDP1CYP2C19
Ammonia Solution, Strong SCHEMBL9302589 0.78 GRIK1 (0.32) GRIK1GRIK2CYP3A4TDP1CYP2C19
SCHEMBL7197484 0.78
SCHEMBL6394457 0.78 MAPT (0.38) CYP3A4TDP1TSHRMAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110386827-A A kind of reverse foamed material and its preparation method and application 中国科学院金属研究所 2019-10-29 CN claimed
CN-109627011-A A kind of preparation method and porous ceramics of the porous ceramics with concentric holes 萍乡学院 2019-04-16 CN claimed
CN-104451222-B A kind of preparation method of nanograined W-Cu composite block material 中南大学 2016-10-19 CN claimed
CN-101972852-B Method for preparing molybdenum part with complex shape UNIV CENTRAL SOUTH 2012-04-25 CN claimed
CN-101979191-B Method for preparing molybdenum copper part with complex shape UNIV CENTRAL SOUTH 2011-12-14 CN claimed
CN-102015293-A Water-based barrier coating compositions MEADWESTVACO CORP 2011-04-13 CN claimed
CN-101979191-A Method for preparing molybdenum copper part with complex shape UNIV CENTRAL SOUTH 2011-02-23 CN claimed
CN-101972852-A Method for preparing complex molybdenum part UNIV CENTRAL SOUTH 2011-02-16 CN claimed
CN-1465405-A Method for making medical aquogel 吉林富华医用高分子材料有限公司 2004-01-07 CN claimed
CN-2536191-Y Adjustable skin smoothing device without water injector CAO MENGJUN (CN) 2003-02-19 CN claimed
CN-2465675-Y Hydrogel mammary prosthesis CAO MENGJUN (CN) 2001-12-19 CN claimed
JP-58096614-A None JP disclosed
CN-115052958-A Lubricating composition and method of operating an internal combustion engine 路博润公司 2022-09-13 CN disclosed
CN-113412422-A Sensor chip and method thereof 新加坡国立大学 2021-09-17 CN disclosed
CN-110386827-A A kind of reverse foamed material and its preparation method and application 中国科学院金属研究所 2019-10-29 CN disclosed
US-20050014830-A1 Substances for breaking down conformation of microbes NATIONAL TAIWAN UNIVERSITY (TW) 2005-01-20 US disclosed
CN-1465405-A Method for making medical aquogel 吉林富华医用高分子材料有限公司 2004-01-07 CN disclosed
CN-2536191-Y Adjustable skin smoothing device without water injector CAO MENGJUN (CN) 2003-02-19 CN disclosed
CN-2465675-Y Hydrogel mammary prosthesis CAO MENGJUN (CN) 2001-12-19 CN disclosed
JP-S5896614-A CURED RESIN TOKUYAMA SODA CO LTD 1983-06-08 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014830-A1 Substances for breaking down conformation of microbes CD14, FABP2, MIF GRIK1 2314/4885GRIK2 2260/4885CYP3A4 3025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.