Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.57 |
| ▸ | TEK | Q02763 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.49 |
| ▸ | TNNI3K | Q59H18 | 7/20 | 0.49 |
| ▸ | BRAF | P15056 | 5/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352526 | 0.91 | KDR (0.60) | KDRTEKNPC1MAPTSAE1 | |
| SCHEMBL5349903 | 0.90 | KDR (0.71) | KDRTEKNPC1MAPTMAPK14 | |
| SCHEMBL7013365 | 0.90 | KDR (0.58) | KDRTEKNPC1MAPTSAE1 | |
| SCHEMBL5466696 | 0.82 | MAPT (0.55) | KDRTEKNPC1MAPTSAE1 | |
| SCHEMBL5349168 | 0.81 | TEK (0.79) | KDRTEKCDK8 | |
| SCHEMBL7017029 | 0.80 | KDR (0.65) | KDRTEKMAPTMAPK14TNNI3K | |
| SCHEMBL5357494 | 0.80 | KDR (0.86) | KDRTEKMAPK14TNNI3KBRAF | |
| SCHEMBL5350261 | 0.80 | KDR (0.70) | KDRTEKMAPK14TNNI3K | |
| SCHEMBL7017943 | 0.80 | KDR (0.71) | KDRTEKMAPK14TNNI3KBRAF | |
| SCHEMBL5348189 | 0.79 | TEK (0.88) | KDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249600-A1 | CHEMICAL COMPOUNDS | CHEUNG MUI | 2007-10-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249600-A1 | CHEMICAL COMPOUNDS | TIE1, KDR, FLT4 | KDR 2/4885TEK 5/4885NPC1 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.