Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14431532 | 0.86 | FFAR1 (0.41) | FFAR1MTNR1AMTNR1BITGB1ITGA4 | |
| SCHEMBL5473946 | 0.83 | MEN1 (0.48) | GAAMTNR1AMTNR1BITGB1ITGA4 | |
| SCHEMBL24934106 | 0.80 | AAK1 (0.40) | MTNR1AMTNR1BALDH1A1TSHRPOLB | |
| SCHEMBL8770380 | 0.80 | AAK1 (0.40) | MTNR1AMTNR1BALDH1A1TSHRPTGDR2 | |
| SCHEMBL24933585 | 0.80 | AAK1 (0.57) | GAAALDH1A1PTGDR2POLBMAPT | |
| SCHEMBL926197 | 0.79 | SCN9A (0.46) | GAAPPARDAAK1 | |
| SCHEMBL12697638 | 0.77 | PLA2G4B (0.56) | PPARDRXRARXRBRXRGPOLB | |
| SCHEMBL6581250 | 0.76 | LMNA (0.42) | MTNR1AMTNR1BMAPTCYP2C9CYP2C19 | |
| SCHEMBL964651 | 0.76 | RXRA (0.48) | GAAPPARDRXRARXRBRXRG | |
| SCHEMBL5472921 | 0.76 | PLA2G4B (0.57) | FFAR1PPARDPPARAPPARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197626-A1 | Indoline derivatives | BAYER HEALTHCARE AG (DE) | 2007-08-23 | — | — | US | disclosed |
| EP-1675825-A2 | INDOLINE DERIVATIVES AS PPAR-DELTA MODULATORS | Bayer HealthCare AG (DE) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005019169-A2 | INDOLINE DERIVATIVES AS PPAR-DELTA MODULATORS | BAYER HEALTHCARE AG (DE) | 2005-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197626-A1 | Indoline derivatives | PPARD, PPARA, PPARG | GAA 3390/4885FFAR1 104/4885MTNR1A 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.