Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 16/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453269 | 0.91 | CYP3A4 (0.63) | CYP3A4CYP2D6MAOAMAOBCYP2C9 | |
| SCHEMBL5460223 | 0.87 | MAOA (0.49) | CYP3A4CYP2D6MAOAMAOBCYP2C9 | |
| SCHEMBL5461284 | 0.86 | MAOA (0.62) | CYP3A4CYP2D6MAOAMAOBCYP2C9 | |
| SCHEMBL5454936 | 0.85 | MAOA (0.54) | CYP3A4CYP2D6MAOAMAOBKCNH2 | |
| SCHEMBL5462815 | 0.85 | MAOA (0.62) | CYP3A4CYP2D6MAOAMAOBCYP2C9 | |
| SCHEMBL3328493 | 0.82 | CYP3A4 (0.79) | CYP3A4CYP2D6MAOAMAOBCYP2C9 | |
| SCHEMBL3328495 | 0.82 | CYP3A4 (0.79) | CYP3A4CYP2D6MAOAMAOBCYP2C9 | |
| SCHEMBL3328501 | 0.82 | CYP3A4 (0.79) | CYP3A4CYP2D6MAOAMAOBCYP2C9 | |
| SCHEMBL5461288 | 0.78 | MAOA (0.53) | CYP3A4CYP2D6MAOAMAOBCYP2C9 | |
| SCHEMBL5238263 | 0.77 | MAOA (0.72) | CYP3A4CYP2D6MAOAMAOBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293493-A1 | OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2007-12-20 | — | — | US | claimed |
| US-20070293493-A1 | OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293493-A1 | OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | OXA1L, RORC, IL17A | CYP3A4 154/4885CYP2D6 91/4885MAOA 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.