Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | ADA | P00813 | 4/20 | 0.52 |
| ▸ | PDE2A | O00408 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28863078 | 1.00 | GSK3B (0.63) | GSK3BADORA2AADAPDE2ACYP3A4 | |
| SCHEMBL29274097 | 0.83 | GSK3B (0.73) | GSK3BADORA2AALDH1A1ADCY5ADORA1 | |
| SCHEMBL16056536 | 0.77 | FGFR1 (0.52) | ADORA2AADAPDE2ACYP3A4ALDH1A1 | |
| SCHEMBL16056781 | 0.77 | FGFR1 (0.52) | ADORA2AADAPDE2ACYP3A4ALDH1A1 | |
| SCHEMBL12112267 | 0.77 | GSK3B (0.37) | GSK3BADAPDE2ACYP3A4ALDH1A1 | |
| SCHEMBL15214201 | 0.77 | GSK3B (0.37) | GSK3BADAPDE2ACYP3A4ALDH1A1 | |
| SCHEMBL3630349 | 0.75 | GSK3B (0.65) | GSK3BADORA2AALDH1A1ADCY5ADORA1 | |
| SCHEMBL5347874 | 0.75 | PNP (0.50) | HSD17B10TSHRBLM | |
| SCHEMBL12112264 | 0.75 | PDE4A (0.36) | GSK3BADORA2AALDH1A1PDE4APDE4B | |
| SCHEMBL9222291 | 0.75 | TMIGD3 (0.58) | ADORA2ASMN1; SMN2TSHRADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017164615-A1 | METHOD FOR PREPARING 3'-AMINO-2',3'-DIDEOXYADENOSINE BY USING NUCLEOSIDE PHOSPHORYLASE DERIVED FROM BACILLUS | ST PHARM CO., LTD. (KR) | 2017-09-28 | — | — | WO | disclosed |
| US-20070065922-A1 | Biocatalytic synthesis of aminodeoxy purine N9-beta-D-nucleosides containing 3-amino-3-deoxy-beta-D-ribofuranose, 3-amino-2,3-dideoxy-beta-D-ribofuranose, and 2-amino-2-deoxy-beta-D-ribofuranose as sugar moieties | METKINEN OY (FI) | 2007-03-22 | — | — | US | disclosed |
| US-4145531-A | Process for producing 2'-substituted-D-ribofuranosyl purine compounds | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 1979-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070065922-A1 | Biocatalytic synthesis of aminodeoxy purine N9-beta-D-nucleosides containing 3-amino-3-deoxy-beta-D-ribofuranose, 3-amino-2,3-dideoxy-beta-D-ribofuranose, and 2-amino-2-deoxy-beta-D-ribofuranose as sugar moieties | DUT, UNG, GALE | GSK3B 1659/4885ADORA2A 264/4885ADA 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.