SCHEMBL5469249

SCHEMBL5469249

CN1CCc2ccc(N3C[C@H](NC(=O)c4ccc(Cl)s4)[C@@H](CCCC(=O)O)C3=O)cc2CC1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 0.43
F2 P00734 4/20 0.43
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
F11 P03951 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14582534 0.97 F10 (0.43) F10F2LMNAMAPK1KMT2A
SCHEMBL14582532 0.96 F10 (0.44) F10F2LMNAMAPK1KMT2A
SCHEMBL5472393 0.92 F10 (0.42) F10F2LMNAMAPK1KMT2A
SCHEMBL5472527 0.92 F10 (0.45) F10F2LMNAMAPK1KMT2A
SCHEMBL5475952 0.91 F10 (0.45) F10F2LMNAMAPK1KMT2A
SCHEMBL14582530 0.89 F10 (0.43) F10F2LMNAMAPK1KMT2A
SCHEMBL5470291 0.89 F10 (0.44) F10F2LMNAMAPK1KMT2A
SCHEMBL5474672 0.89 F10 (0.47) F10F2LMNAMAPK1KMT2A
SCHEMBL5475634 0.89 F10 (0.42) F10F2LMNAMAPK1KMT2A
SCHEMBL14582531 0.87 F10 (0.43) F10F2LMNAMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070032473-A1 Substituted amides and their use as medicaments GERLACH KAI 2007-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032473-A1 Substituted amides and their use as medicaments OAT, HLA-B, BCAT2 F10 1757/4885F2 461/4885LMNA 1681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.