Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 12/20 | 0.73 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5096270 | 0.91 | PTGER1 (0.64) | PTGER1MCL1FOLH1NPC1LMNA | |
| SCHEMBL5099647 | 0.88 | PTGER1 (0.64) | PTGER1MCL1FOLH1NPC1LMNA | |
| SCHEMBL5099812 | 0.84 | PTGER1 (1.00) | PTGER1CYP2C9MRGPRX4 | |
| SCHEMBL1646699 | 0.83 | FOLH1 (0.67) | PTGER1MCL1FOLH1NPC1LMNA | |
| SCHEMBL5933469 | 0.82 | PTGER1 (0.82) | PTGER1CYP2C9MRGPRX4RXRARXRB | |
| SCHEMBL28911191 | 0.80 | MCL1 (0.56) | PTGER1MCL1FOLH1NPC1LMNA | |
| SCHEMBL2453382 | 0.78 | LMNA (0.62) | PTGER1FOLH1NPC1LMNAMAPT | |
| SCHEMBL4638882 | 0.77 | PTGER1 (0.53) | PTGER1MCL1FOLH1CYP2C9MAPT | |
| SCHEMBL5099450 | 0.77 | PTGER1 (0.79) | PTGER1MCL1CYP2C9PTGER4PTGER3 | |
| SCHEMBL2452574 | 0.77 | LMNA (0.68) | FOLH1NPC1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225340-A1 | Phenyl Compounds And Their Use In The Treatment Of Conditions Mediated By The Action Of Pge2 At The Ep1 Receptor | GLAXO GROUP LIMITED (GB) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225340-A1 | Phenyl Compounds And Their Use In The Treatment Of Conditions Mediated By The Action Of Pge2 At The Ep1 Receptor | PTGER1, PTGER2, PTGDR | PTGER1 1/4885MCL1 2490/4885FOLH1 3903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.