Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.59 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1098147 | 0.89 | NR4A2 (0.57) | LMNANR4A2SGMS2MRGPRX4L3MBTL1 | |
| SCHEMBL5839978 | 0.88 | ALDH1A1 (0.54) | LMNASGMS2MRGPRX4NPC1L3MBTL1 | |
| SCHEMBL1646699 | 0.85 | FOLH1 (0.67) | LMNASGMS2MRGPRX4NPC1L3MBTL1 | |
| SCHEMBL28911191 | 0.85 | MCL1 (0.56) | LMNANR4A2MRGPRX4NPC1L3MBTL1 | |
| SCHEMBL1647303 | 0.85 | LRRK2 (0.67) | NR4A2MRGPRX4MAPTFOLH1LRRK2 | |
| SCHEMBL2453770 | 0.85 | SGMS2 (0.58) | LMNASGMS2MRGPRX4NPC1L3MBTL1 | |
| SCHEMBL2452574 | 0.84 | LMNA (0.68) | LMNANR4A2SGMS2NPC1L3MBTL1 | |
| SCHEMBL112903 | 0.84 | SGMS2 (0.66) | LMNASGMS2NPC1L3MBTL1MAPT | |
| SCHEMBL29433417 | 0.84 | SGMS2 (0.66) | LMNASGMS2NPC1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL8998291 | 0.82 | SGMS2 (0.64) | LMNASGMS2NPC1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995567-B | Formamide pyridone iron chelator derivative with potential multi-target anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-111995567-A | Formamide pyridone iron chelator derivative with potential multi-target anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2020-11-27 | — | — | CN | disclosed |
| US-8022072-B2 | Azolylmethylidenehydrazine derivative and use thereof | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-2168951-A1 | AZOLYLMETHYLENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-6984645-B2 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | ARSA, AHR, HRH2 | LMNA 4255/4885NR4A2 285/4885SGMS2 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.