SCHEMBL547080

SCHEMBL547080

C=C(CC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.70
▸ MAPK1 P28482 3/20 0.70
▸ HPGD P15428 3/20 0.70
▸ KMT2A Q03164 3/20 0.70
▸ MEN1 O00255 2/20 0.70
▸ CYP3A4 P08684 2/20 0.70
▸ TDP1 Q9NUW8 2/20 0.70
▸ SMN1; SMN2 Q16637 2/20 0.70
▸ KDM4E B2RXH2 1/20 0.70
▸ ALOX15 P16050 1/20 0.70
▸ CES1 P23141 1/20 0.70
▸ PTPN1 P18031 2/20 0.59
▸ ERCC5 P28715 2/20 0.59
▸ FEN1 P39748 2/20 0.59
▸ ALDH1A1 P00352 4/20 0.57
▸ LMNA P02545 3/20 0.57
▸ USP2 O75604 1/20 0.57
▸ POLB P06746 1/20 0.57
▸ HTT P42858 1/20 0.57
▸ NPSR1 Q6W5P4 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22756231 0.84 USP5 (0.54) MAPTMAPK1HPGDKMT2AMEN1
SCHEMBL156766 0.84 MAOA (0.54) MAPTMAPK1HPGDKMT2AMEN1
Dibenzoylmethane SCHEMBL39582 0.83 MEN1 (1.00) MAPTMAPK1HPGDKMT2AMEN1
Dibenzoylmethane SCHEMBL1704711 0.83 MEN1 (1.00) MAPTMAPK1HPGDKMT2AMEN1
Dibenzoylmethane SCHEMBL10356288 0.83 MEN1 (1.00) MAPTMAPK1HPGDKMT2AMEN1
Dibenzoylmethane SCHEMBL6313817 0.80 MEN1 (0.94) MAPTMAPK1HPGDKMT2AMEN1
Dibenzoylmethane SCHEMBL14249870 0.80 MEN1 (0.94) MAPTMAPK1HPGDKMT2AMEN1
Dibenzoylmethane SCHEMBL11909772 0.80 MEN1 (0.94) MAPTMAPK1HPGDKMT2AMEN1
Dibenzoylmethane SCHEMBL21597905 0.80 MEN1 (0.94) MAPTMAPK1HPGDKMT2AMEN1
Dibenzoylmethane SCHEMBL11740368 0.80 MEN1 (0.94) MAPTMAPK1HPGDKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500255-B Synthesis method of 1, 3-disubstituted indene compounds 温州大学 2022-09-20 — — CN disclosed
CN-112500255-A Synthesis method of 1, 3-disubstituted indene compounds 温州大学 2021-03-16 — — CN disclosed
WO-2020118933-A1 NOVEL POLYCYCLIC COMPOUND 优缔新材料科技(苏州)有限公司 2020-06-18 — — WO disclosed
US-20160244409-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof CORAL SUNSCREEN PTY LTD (AU) 2016-08-25 — — US disclosed
EP-1739104-B1 POLYMER-SUPPORTED METAL CLUSTER COMPOSITIONS JAPAN SCIENCE & TECH AGENCY (JP) 2014-07-09 — — EP disclosed
US-8110519-B2 Coordination catalyst on crosslinked catalsy support; recoverable , reuse; hydrogenation catalyst, oxidation catalyst, coupling, carbonylation JAPAN SCIENCE & TECHNOLOGY AGENCY (JP) 2012-02-07 — — US disclosed
US-20080058200-A1 Polymer-Supported Metal Cluster Composition JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2008-03-06 — — US disclosed
EP-1739104-A1 POLYMER-SUPPORTED METAL CLUSTER COMPOSITIONS Japan Science and Technology Agency (JP) 2007-01-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160244409-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof ERCC4, ERCC1, ERCC5 MAPT 91/4885MAPK1 4421/4885HPGD 479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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