SCHEMBL547105

SCHEMBL547105

CCCCCCCCC(Cc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGES O14684 3/20 0.41
ALOX5 P09917 3/20 0.41
PPARG P37231 3/20 0.41
HDAC8 Q9BY41 5/20 0.36
HDAC3 O15379 3/20 0.36
HDAC6 Q9UBN7 3/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
FOLH1 Q04609 1/20 0.36
F2R P25116 1/20 0.36
MAPT P10636 1/20 0.35
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
CSNK1E P49674 1/20 0.34
MMP2 P08253 6/20 0.34
MMP1 P03956 2/20 0.34
HDAC4 P56524 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30772441 0.96 FOLH1 (0.39) PTGESALOX5PPARGHDAC8HDAC3
SCHEMBL672758 0.96 FOLH1 (0.39) PTGESALOX5PPARGHDAC8HDAC3
SCHEMBL2387522 0.92 FOLH1 (0.36) PTGESALOX5PPARGHDAC8HDAC3
SCHEMBL224451 0.90 PPARG (0.35) PTGESALOX5PPARGGRIK1GRIK2
SCHEMBL207237 0.89 PPARG (0.35) PTGESALOX5PPARGHDAC8HDAC3
SCHEMBL15422728 0.89 PTGES (0.36) PTGESALOX5PPARGFOLH1F2R
SCHEMBL15163389 0.86 PPARG (0.37) PTGESALOX5PPARGFOLH1MAPT
Bumetrizole SCHEMBL9683667 0.84 NPC1 (0.35) PTGESALOX5PPARGF2RMAPT
SCHEMBL4532741 0.83 PPARG (0.36) PTGESALOX5PPARGFOLH1MAPT
SCHEMBL132430 0.82 MAOB (0.39) PPARGF2RMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1252227-B1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE CIBA SC HOLDING AG (CH) 2004-09-22 EP claimed
US-6540795-B2 Stabilized against discoloration and fading CIBA SPECIALTY CHEMICALS CORPORATION 2003-04-01 US claimed
CN-112041368-B Blue light cut-off optical material with bluish appearance 依视路国际公司 2022-07-05 CN disclosed
CN-108603946-B Blue light blocking optical materials comprising benzotriazole UV absorbers 依视路国际公司 2021-07-27 CN disclosed
CN-112041368-A Blue light cut-off optical material with bluish appearance 依视路国际公司 2020-12-04 CN disclosed
EP-3039089-B1 FORMABLE AMINOPLAST RESIN-BASED COATING COMPOSITIONS SDC TECH INC (US) 2018-02-07 EP disclosed
EP-2188669-B1 ELECTROFLUIDIC DEVICES, VISUAL DISPLAYS, AND METHODS FOR MAKING AND OPERATING SUCH ELECTROFLUIDIC DEVICES UNIV CINCINNATI (US) 2017-01-11 EP disclosed
US-9181451-B2 Formable aminoplast resin-based coating compositions SDC TECHNOLOGIES, INC. (US) 2015-11-10 US disclosed
US-20150218393-A1 STABLE UV ABSORBER COMPOSITION BASF SE (DE) 2015-08-06 US disclosed
EP-2885355-A1 STABLE UV ABSORBER COMPOSITION BASF SE (DE) 2015-06-24 EP disclosed
US-20150064457-A1 FORMABLE AMINOPLAST RESIN-BASED COATING COMPOSITIONS SDC TECHNOLOGIES, INC. (US) 2015-03-05 US disclosed
EP-0695318-A1 INCREASING THE MOLECULAR WEIGHT OF POLYESTERS AND PREMIX USEFUL FOR THIS PROCESS Ciba SC Holding AG (CH) 1996-02-07 EP disclosed
WO-1995033004-A1 POLYESTER/POLYCARBONATE BLENDS HAVING ENHANCED PROPERTIES CIBA SC HOLDING AG (CH) 1995-12-07 WO disclosed
EP-0670842-A1 BETA CRYSTALLINE MODIFICATION OF 2,2',2''-NITRILO TRIETHYL-TRIS-(3,3',5,5'-TETRA-TERT-BUTYL-1,1'-BIPHENYL-2,2'-DIYL) PHOSPHITE]. CIBA GEIGY AG (CH) 1995-09-13 EP disclosed
WO-1995023176-A1 INCREASING THE MOLECULAR WEIGHT OF POLYESTERS CIBA-GEIGY AG (CH) 1995-08-31 WO disclosed
EP-0662105-A1 PROCESS FOR THE STABILIZATION OF AND STABILIZER MIXTURES FOR SINGLE-MATERIAL RECYCLED PLASTICS Ciba SC Holding AG (CH) 1995-07-12 EP disclosed
WO-1995005387-A1 GAMMA CRYSTALLINE MODIFICATION OF 2,2',2'-NITRILO[TRIETHYL-TRIS-(3,3',5,5'-TETRA-TERT-BUTYL-1,1'-BIPHENYL-2,2'-DIYL)PHOSPHITE] CIBA-GEIGY AG (CH) 1995-02-23 WO disclosed
WO-1994024188-A1 INCREASING THE MOLECULAR WEIGHT OF POLYESTERS AND PREMIX USEFUL FOR THIS PROCESS CIBA-GEIGY AG (CH) 1994-10-27 WO disclosed
WO-1994012508-A1 BETA CRYSTALLINE MODIFICATION OF 2,2',2''-NITRILO[TRIETHYL-TRIS-(3,3',5,5'-TETRA-TERT-BUTYL-1,1'-BIPHENYL-2,2'-DIYL) PHOSPHITE] CIBA-GEIGY AG (CH) 1994-06-09 WO disclosed
WO-1994007951-A1 PROCESS FOR THE STABILIZATION OF AND STABILIZER MIXTURES FOR SINGLE-MATERIAL RECYCLED PLASTICS CIBA-GEIGY AG (CH) 1994-04-14 WO disclosed