SCHEMBL547108

SCHEMBL547108

C=CC[Si](CC=C)(CC=C)OC(=O)C=C

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.38
ALDH1A1 P00352 5/20 0.38
TP53 P04637 3/20 0.38
HIF1A Q16665 3/20 0.38
CYP3A4 P08684 2/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 1/20 0.34
FGFR4 P22455 1/20 0.33
MAPT P10636 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7591793 0.78 ALDH1A1 (0.35) TSHRALDH1A1FGFR4MAPTCACNA1B
SCHEMBL4563189 0.76 ALDH1A1 (0.32) ALDH1A1MAPTCACNA1BAPBA1
SCHEMBL1900219 0.76 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2873372 0.74 ALDH1A1 (0.42) TSHRALDH1A1
SCHEMBL1447931 0.73
SCHEMBL5838940 0.73 TSHR (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4830318 0.73 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8522493 0.71
SCHEMBL9082756 0.71 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28656323 0.70 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110982018-B Silane-modified high-molecular stabilizer and preparation method and application thereof 浙江传化功能新材料有限公司 2022-06-24 CN claimed
CN-110982018-A Silane-modified high-molecular stabilizer and preparation method and application thereof 杭州传化精细化工有限公司 2020-04-10 CN claimed
EP-2161318-A1 TRIPHENYLBORON COMPOUND-CONTAINING ANTIFOULING COATING COMPOSITION HAVING IMPROVED STABILITY, ANTIFOULING AGENT SET USED THEREFOR, AND METHOD FOR SUPPRESSING/CONTROLLING DECOMPOSITION OF TRIPHENYLBORON COMPOUND CHUGOKU MARINE PAINTS, LTD. (JP) 2010-03-10 EP claimed
EP-1295888-A1 Process for the preparation of trialkylsilylated carboxylate monomers, the obtained trialkylsilylated carboxylate monomers and their use in antifouling coatings SIGMA COATINGS B.V. (NL) 2003-03-26 EP claimed
US-5328973-A Acid labile protecting groups are cleaved by strong acid formed by ultraviolet radiation, solubility of polymer is changed HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-12 US claimed
US-4576864-A Water spreading plastic material, method for its manufacture and its use as a glazing and roofing material ROHM GMBH CHEMISCHE FABRIK (DE) 1986-03-18 US claimed
CN-113444418-B Antifouling coating composition 中国涂料株式会社 2024-02-13 CN disclosed
CN-110982018-B Silane-modified high-molecular stabilizer and preparation method and application thereof 浙江传化功能新材料有限公司 2022-06-24 CN disclosed
CN-110982018-B Silane-modified high-molecular stabilizer and preparation method and application thereof 浙江传化功能新材料有限公司 2022-06-24 CN disclosed
CN-113444418-A Antifouling coating composition 中国涂料株式会社 2021-09-28 CN disclosed
CN-109906254-B Antifouling coating composition, antifouling coating film, substrate with antifouling coating film, method for producing substrate with antifouling coating film, and antifouling method 中国涂料株式会社 2021-08-24 CN disclosed
EP-2921538-B1 ANTIFOULING COATING COMPOSITION, ANTIFOULING COATING FILM, ANTIFOULING SUBSTRATE, AND METHOD FOR IMPROVING STORAGE STABILITY OF ANTIFOULING COATING COMPOSITION CHUGOKU MARINE PAINTS (JP) 2021-01-27 EP disclosed
EP-3228390-B1 METHOD FOR REINFORCING CONTAMINATION-RESISTANT FILM CHUGOKU MARINE PAINTS (JP) 2020-12-23 EP disclosed
US-20020197490-A1 Curable composition, coating composition, paint, antifouling paint, cured product thereof and method of rendering base material antifouling AMIDAIJI KATSUYOSHI (JP) 2002-12-26 US disclosed
US-6451437-B1 AN ORGANOPOLYSILOXANE HAVING FUNCTIONAL GROUPS CAPABLE OF CONDENSATION REACTION AT BOTH MOLECULAR TERMINALS, HYDROPHOBIC SILICA AND A HYDROPHILIC SILICA; UNDERWATER STRUCTURE OR A SHIP SHELL PLATE. CHUGOKU MARINE PAINTS, LTD. (JP) 2002-09-17 US disclosed
EP-1092758-A2 Curable composition, coating composition, paint, antifouling paint, cured product thereof and method of rendering base material antifouling CHUGOKU MARINE PAINTS, LTD. (JP) 2001-04-18 EP disclosed
US-5328973-A Acid labile protecting groups are cleaved by strong acid formed by ultraviolet radiation, solubility of polymer is changed HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-12 US disclosed
EP-0297505-B1 ANTIFOULING PAINT NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-09-02 EP disclosed
US-5116611-A Siloxane polymers NIPPON OIL AND FATS COMPANY LIMITED (JP) 1992-05-26 US disclosed
EP-0364272-A2 Coating compositions COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) 1990-04-18 EP disclosed