SCHEMBL4563189

SCHEMBL4563189

C=CC[Si](CC=C)(CC=C)OC(=O)CC(=O)O[Si](CC=C)(CC=C)CC=C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6396994 0.88 TSHR (0.40) ALDH1A1MAPTCACNA1BAPBA1
SCHEMBL2873372 0.79 ALDH1A1 (0.42) ALDH1A1
SCHEMBL16325170 0.79 ALDH1A1 (0.43) ALDH1A1LMNA
SCHEMBL7591793 0.78 ALDH1A1 (0.35) ALDH1A1MAPTCACNA1BAPBA1
SCHEMBL547108 0.76 TSHR (0.38) ALDH1A1MAPTCACNA1BAPBA1
SCHEMBL8526595 0.74
SCHEMBL8522493 0.71
SCHEMBL6684643 0.70 ALDH1A1 (0.41) ALDH1A1MAPT
SCHEMBL1447931 0.68
SCHEMBL11031272 0.67 ALDH1A1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534908-B2 Method for the production of optically active 3-alkylcarboxylic acids and the intermediate products thereof WACKER CHEMIE AG (DE) 2009-05-19 US disclosed
EP-1142894-B1 Volatile precursors for deposition of metals and metal-containing films AIR PROD & CHEM (US) 2005-01-12 EP disclosed
US-6818783-B2 HOMOLOGOUS EIGHT MEMBERED RING COMPOUNDS HAVING A METAL, SUCH AS COPPER, REVERSIBLY BOUND IN THE RING AND CONTAINING CARBON, NITROGEN, SILICON AND/OR OTHER METALS. AIR PRODUCTS AND CHEMICALS, INC. 2004-11-16 US disclosed
US-20040215030-A1 Precursors for metal containing films VERSUM MATERIALS US, LLC 2004-10-28 US disclosed
EP-1471568-A1 Precursors for metal containing films AIR PRODUCTS AND CHEMICALS, INC. (US) 2004-10-27 EP disclosed
US-20030135061-A1 Volatile precursors for deposition of metals and metal-containing films VERSUM MATERIALS US, LLC 2003-07-17 US disclosed
US-20020013487-A1 Volatile precursors for deposition of metals and metal-containing films VERSUM MATERIALS US, LLC 2002-01-31 US disclosed
EP-1142894-A2 Volatile precursors for deposition of metals and metal-containing films AIR PRODUCTS AND CHEMICALS, INC. (US) 2001-10-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013487-A1 Volatile precursors for deposition of metals and metal-containing films SOD1, C1R, C5 ALDH1A1 183/4885LMNA 837/4885MAPT 1670/4885
US-20030135061-A1 Volatile precursors for deposition of metals and metal-containing films SOD1, C1R, C5 ALDH1A1 183/4885LMNA 695/4885MAPT 1833/4885
US-20040215030-A1 Precursors for metal containing films TBL3, TBL2, TNNI3 ALDH1A1 1816/4885LMNA 205/4885MAPT 880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.