Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554110 | 0.88 | CYP2A6 (0.44) | KDM4EALDH1A1MAPTLMNAALOX15 | |
| SCHEMBL548410 | 0.84 | CYP2A6 (0.50) | KDM4EALDH1A1MAPTSMN1; SMN2CA9 | |
| SCHEMBL11831965 | 0.82 | KDM4E (0.82) | KDM4EALDH1A1MAPTLMNAALOX15 | |
| SCHEMBL30482504 | 0.80 | KCNH2 (0.40) | KDM4EALDH1A1MAPTLMNAALOX15 | |
| SCHEMBL16905653 | 0.80 | CYP2A6 (0.39) | KDM4EALDH1A1MAPTLMNAALOX15 | |
| SCHEMBL16906001 | 0.80 | IDO1 (0.45) | KDM4EALDH1A1MAPTSMN1; SMN2HSD17B3 | |
| SCHEMBL548396 | 0.80 | IDO1 (0.45) | KDM4EALDH1A1MAPTLMNAALOX15 | |
| SCHEMBL16558189 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5479951 | 0.78 | CYP2A6 (0.40) | KDM4EALDH1A1ESR2CA9CA12 | |
| SCHEMBL3874542 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1MAPTLMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070093548-A1 | Use of progesterone receptor modulators | WYETH (US) | 2007-04-26 | — | — | US | claimed |
| US-20070093548-A1 | Use of progesterone receptor modulators | WYETH (US) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093548-A1 | Use of progesterone receptor modulators | PGR, GNRHR, PGRMC2 | KDM4E 4166/4885ALDH1A1 2280/4885MAPT 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.