SCHEMBL16558189

SCHEMBL16558189

N#Cc1ccc2oc3ccccc3c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
ALDH1A1 P00352 4/20 0.53
MAPT P10636 4/20 0.53
HPGD P15428 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
NPC1 O15118 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
RAB9A P51151 1/20 0.53
TNKS O95271 1/20 0.51
AHR P35869 2/20 0.48
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
CYP2A6 P11509 1/20 0.43
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
NOS2 P35228 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17827373 0.93 TNKS (0.54) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL548410 0.90 CYP2A6 (0.50) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL3086890 0.89 AHR (0.53) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL11554110 0.86 CYP2A6 (0.44) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL13171162 0.86 TNKS (0.57) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL31161245 0.86 MAOA (0.60) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL11373382 0.86 MAOA (0.60) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL21691240 0.85 PGR (0.49) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL13171082 0.84 TNKS (0.49) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL21692161 0.84 TNKS (0.46) KDM4EALDH1A1MAPTHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768164-A Pharmaceutical compounds for treating complement-mediated disorders 阿雷克森制药公司 2025-04-04 CN disclosed
CN-116199599-B Method for preparing aryl nitrile compound 江苏师范大学 2024-11-15 CN disclosed
CN-116903493-A Method for synthesizing polysubstituted o-phenylphenol compound through nucleophilic reaction ring opening of dibenzofuran 华南理工大学 2023-10-20 CN disclosed
CN-116199599-A Method for preparing aryl nitrile compound 江苏师范大学 2023-06-02 CN disclosed
US-20230071261-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-03-09 US disclosed
US-11174258-B2 Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2021-11-16 US disclosed
US-11005050-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-05-11 US disclosed
EP-3109231-B1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2019-10-16 EP disclosed
US-20190002469-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2019-01-03 US disclosed
US-9825231-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-21 US disclosed
EP-3094638-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2017-11-08 EP disclosed
US-20170170413-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2017-06-15 US disclosed
US-20170170413-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2017-06-15 US disclosed
WO-2017093958-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2017-06-08 WO disclosed
US-20160365520-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2016-12-15 US disclosed
US-20160365520-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2016-12-15 US disclosed
WO-2015117718-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2015-08-13 WO disclosed
WO-2015104045-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2015-07-16 WO disclosed
US-20150069347-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-03-12 US disclosed
US-20150069347-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11174258-B2 Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes KCNH2, KCNH3, KCNJ2 KDM4E 1039/4885ALDH1A1 397/4885MAPT 2580/4885
US-20190002469-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES KCNH2, KCNH3, KCNJ2 KDM4E 1039/4885ALDH1A1 397/4885MAPT 2580/4885
US-11005050-B2 Metal complexes SOD1, AP1M1, AP3M1 KDM4E 3816/4885ALDH1A1 3721/4885MAPT 1084/4885
US-20160365520-A1 METAL COMPLEXES SOD1, AP1M1, AP3M1 KDM4E 3816/4885ALDH1A1 3721/4885MAPT 1084/4885
US-20170170413-A1 METAL COMPLEXES SOD1, AP1M1, AP3M1 KDM4E 3816/4885ALDH1A1 3721/4885MAPT 1084/4885
US-20230071261-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LOXL1, OCIAD2 KDM4E 3634/4885ALDH1A1 43/4885MAPT 3279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.