Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458833 | 0.88 | FNTA (0.46) | TDP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL5468515 | 0.83 | TDP1 (0.50) | TDP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL3291470 | 0.81 | ALDH1A1 (0.48) | TDP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL5463173 | 0.81 | ALDH1A1 (0.52) | TDP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL3297498 | 0.81 | ALDH1A1 (0.50) | TDP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL5456318 | 0.80 | LAP3 (0.54) | TDP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL5469494 | 0.79 | ALDH1A1 (0.41) | TDP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL5318777 | 0.78 | HPGD (0.44) | TDP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL14001445 | 0.78 | TDP1 (0.44) | TDP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL5478001 | 0.76 | RNPEP (0.42) | TDP1ALDH1A1MAPTLMNAMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | MALLE GERARD | 2007-01-11 | — | — | US | claimed |
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | L'OREAL S.A. (FR) | 2005-09-15 | — | — | US | claimed |
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | MALLE GERARD | 2007-01-11 | — | — | US | disclosed |
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | L'OREAL S.A. (FR) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | NR5A1, SRD5A2, HRH3 | TDP1 2922/4885ALDH1A1 792/4885HPGD 487/4885 |
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | NR5A1, SRD5A2, HRH3 | TDP1 2922/4885ALDH1A1 792/4885HPGD 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.