Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5476620 | 1.00 | SLC6A4 (0.48) | SLC6A4SLC6A2OPRL1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL5473284 | 0.99 | SLC6A4 (0.47) | SLC6A4SLC6A2OPRL1OPRM1OPRK1 | |
| SCHEMBL5476303 | 0.92 | SLC6A4 (0.48) | SLC6A4SLC6A2OPRL1OPRM1OPRK1 | |
| SCHEMBL5476855 | 0.92 | SLC6A4 (0.48) | SLC6A4SLC6A2OPRL1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL5472496 | 0.91 | SLC6A4 (0.47) | SLC6A4SLC6A2OPRL1OPRM1OPRK1 | |
| SCHEMBL4718968 | 0.91 | SLC6A2 (0.48) | SLC6A4SLC6A2OPRL1OPRM1OPRK1 | |
| SCHEMBL5473093 | 0.87 | SLC6A2 (0.55) | SLC6A4SLC6A2 | |
| SCHEMBL5481584 | 0.87 | SLC6A2 (0.55) | SLC6A4SLC6A2 | |
| SCHEMBL5476343 | 0.86 | SLC6A2 (0.49) | SLC6A4SLC6A2 | |
| SCHEMBL5481137 | 0.86 | SLC6A2 (0.49) | SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2007-03-29 | — | — | US | claimed |
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072897-A1 | Phenylaminopropanol derivatives and methods of their use | COMT, PNMT, GLS | SLC6A4 16/4885SLC6A2 8/4885OPRL1 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.