SCHEMBL54737

SCHEMBL54737

COc1ccccc1NC(=O)CC(C)=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.69
MEN1 O00255 3/20 0.69
ALDH1A1 P00352 4/20 0.65
POLB P06746 2/20 0.65
MAPT P10636 2/20 0.61
HSD17B10 Q99714 1/20 0.61
LMNA P02545 1/20 0.61
USP2 O75604 1/20 0.61
TSHR P16473 1/20 0.61
HTT P42858 1/20 0.60
HDAC3 O15379 1/20 0.60
HDAC4 P56524 1/20 0.60
HDAC1 Q13547 1/20 0.60
HDAC7 Q8WUI4 1/20 0.60
HDAC2 Q92769 1/20 0.60
HDAC10 Q969S8 1/20 0.60
HDAC11 Q96DB2 1/20 0.60
HDAC8 Q9BY41 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60
HDAC9 Q9UKV0 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31590799 1.00 KMT2A (0.69) KMT2AMEN1ALDH1A1POLBMAPT
SCHEMBL7747949 0.92 HDAC3 (0.72) KMT2AMEN1ALDH1A1POLBMAPT
SCHEMBL2007035 0.91 MEN1 (0.76) KMT2AMEN1ALDH1A1POLBMAPT
4-Chloroaniline SCHEMBL9317061 0.86 MEN1 (0.64) KMT2AMEN1ALDH1A1POLBMAPT
SCHEMBL29389614 0.86 KMT2A (0.74) KMT2AMEN1ALDH1A1POLBMAPT
SCHEMBL306869 0.86 KMT2A (0.74) KMT2AMEN1ALDH1A1POLBMAPT
SCHEMBL1645833 0.86 ADRA2C (0.67) KMT2AMEN1ALDH1A1POLBMAPT
SCHEMBL28046011 0.85 ALDH1A1 (0.55) KMT2AMEN1ALDH1A1POLBMAPT
SCHEMBL4593391 0.85 MAPT (0.73) KMT2AMEN1ALDH1A1POLBMAPT
SCHEMBL11447231 0.85 ALDH1A1 (0.68) KMT2AMEN1ALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 656 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022228846-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-11-03 WO claimed
WO-2022117389-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-06-09 WO claimed
CN-113717546-A Method for preparing organic pigment yellow and pigment orange by modifying attapulgite 宇虹颜料股份有限公司 2021-11-30 CN claimed
US-10800922-B2 Pigment composition production method KAO CORPORATION (JP) 2020-10-13 US claimed
US-10739691-B2 Electrostatic image developing toner and developer Konica Minolta, Inc. (JP) 2020-08-11 US claimed
CN-108137939-B Method for producing pigment composition 花王株式会社 2020-06-05 CN claimed
CN-111190332-A Toner for developing electrostatic image and laminated glass 柯尼卡美能达株式会社 2020-05-22 CN claimed
US-20200150551-A1 ELECTROSTATIC IMAGE DEVELOPING TONER AND DEVELOPER Konica Minolta, Inc. (JP) 2020-05-14 US claimed
CN-108137938-B Method for producing pigment composition 花王株式会社 2020-03-20 CN claimed
EP-3561003-A1 A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-10-30 EP claimed
EP-0263951-A2 Disazo compounds and compositions containing them BASF Lacke + Farben AG (DE) 1988-04-20 EP claimed
US-4643770-A TETRAZOTIZED 3,3'-DICHLOROBENZIDINE REACTED WITH ACETOACETARYLIDIDE AND KETIMINE BASF CORPORATION, INMONT DIVISION (US) 1987-02-17 US claimed
EP-0097912-B1 Use of diaryl pigments for the pigmentation of plastics HOECHST AKTIENGESELLSCHAFT (DE) 1987-01-14 EP claimed
US-4602960-A Modified diarylide pigments and their preparation BASF FARBEN & FASERN AKTIENGESELLSCHAFT (DE) 1986-07-29 US claimed
EP-0079303-B1 STABILIZED COVERING FORM OF CI PIGMENT YELLOW 74 CIBA-GEIGY AG (CH) 1986-03-05 EP claimed
US-4457783-A Stabilized opaque form of C.I. Pigment Yellow 74 CIBA-GEIGY CORPORATION (US) 1984-07-03 US claimed
US-4204871-A Printing inks containing nucleated organic pigments SUN CHEMICAL CORPORATION (US) 1980-05-27 US claimed
US-4159264-A Automatic control of azo coupling processes in the manufacture of azo pigments CIBA-GEIGY CORPORATION (US) 1979-06-26 US claimed
US-4021240-A DIFFUSION, SILVER HALIDE OXIDIZER EASTMAN KODAK COMPANY (US) 1977-05-03 US claimed
US-3991044-A Process for improving lightfastness of an azo pigment by heat treatment HERCULES INCORPORATED (US) 1976-11-09 US claimed