SCHEMBL5474109

SCHEMBL5474109

O=C(O)C(c1ccccc1)S(=O)(=O)Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 3/20 0.67
CYP2D6 P10635 1/20 0.48
LMNA P02545 3/20 0.46
MAPK1 P28482 1/20 0.46
CYP2C19 P33261 1/20 0.42
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
HSD17B10 Q99714 1/20 0.39
HSD11B1 P28845 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PTPN1 P18031 1/20 0.38
PTPN6 P29350 1/20 0.38
PTPN11 Q06124 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11721467 0.85 SRC (0.53) SRCCYP2D6LMNAMAPK1CYP2C19
SCHEMBL28144339 0.83 SRC (0.52) SRCCYP2D6LMNAMAPK1CYP2C19
SCHEMBL20869602 0.80 SRC (1.00) SRCCYP2D6LMNAMAPK1CYP2C19
SCHEMBL9912818 0.80 SRC (1.00) SRCCYP2D6LMNAMAPK1CYP2C19
SCHEMBL11166146 0.80 SRC (1.00) SRCCYP2D6LMNAMAPK1CYP2C19
SCHEMBL7388431 0.79 KMT2A (0.56) SRCLMNAALDH1A1
SCHEMBL6204480 0.78 SRC (0.67) SRCCYP2D6LMNAMAPK1CYP2C19
SCHEMBL10362230 0.78 SRC (0.67) SRCCYP2D6LMNAMAPK1CYP2C19
SCHEMBL11788287 0.78 SRC (0.67) SRCCYP2D6LMNAMAPK1CYP2C19
SCHEMBL28403215 0.78 SRC (0.96) SRCCYP2D6LMNAMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777061-A Epoxy functionalized lithium sulfonyl imide and preparation method and application thereof 上海交通大学绍兴新能源与分子工程研究院 2024-03-29 CN claimed
US-4026940-A CLEAVING TERT-BUTYL ESTER WITH STRONG ACID TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-05-31 US claimed
CN-117777061-A Epoxy functionalized lithium sulfonyl imide and preparation method and application thereof 上海交通大学绍兴新能源与分子工程研究院 2024-03-29 CN disclosed
US-7312266-B2 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers THE COLLEGE OF WILLIAM AND MARY (US) 2007-12-25 US disclosed
US-6927247-B2 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers THE COLLEGE OF WILLIAM AND MARY (US) 2005-08-09 US disclosed
US-20050049307-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers COLLEGE OF WILLIAM AND MARY, THE 2005-03-03 US disclosed
US-20030220429-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers COLLEGE OF WILLIAM AND MARY, THE 2003-11-27 US disclosed
US-4057544-A BACTERICIDE TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-11-08 US disclosed
US-4026940-A CLEAVING TERT-BUTYL ESTER WITH STRONG ACID TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-05-31 US disclosed
US-3954826-A ANTIBACTERIAL INTERMEDIATES TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050049307-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers TST, LANCL1, TTPA SRC 2137/4885CYP2D6 1623/4885LMNA 4523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.