Methyl P-Hydroxycinnamate

Methyl P-Hydroxycinnamate

SCHEMBL547438

COC(=O)C=Cc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 1.00
CA7 P43166 6/20 1.00
CA9 Q16790 6/20 1.00
CA14 Q9ULX7 6/20 1.00
CA1 P00915 5/20 1.00
CA2 P00918 4/20 1.00
TYR P14679 3/20 1.00
PTPN1 P18031 1/20 0.67
AKR1B10 O60218 4/20 0.66
AKR1B1 P15121 4/20 0.66
TTR P02766 1/20 0.66
APP P05067 1/20 0.66
MAOB P27338 1/20 0.62
PTGS2 P35354 1/20 0.62
GLO1 Q04760 1/20 0.62
CAMK2A Q9UQM7 1/20 0.62
MMP2 P08253 2/20 0.62
MMP9 P14780 2/20 0.62
MMP13 P45452 1/20 0.62
ESR1 P03372 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl P-Hydroxycinnamate SCHEMBL895938 1.00 CA12 (1.00) CA12CA7CA9CA14CA1
Methyl P-Hydroxycinnamate SCHEMBL30463538 1.00 CA12 (1.00) CA12CA7CA9CA14CA1
Methyl P-Hydroxycinnamate SCHEMBL28386655 1.00 CA12 (1.00) CA12CA7CA9CA14CA1
Methyl P-Hydroxycinnamate SCHEMBL28876782 0.96 CA12 (0.93) CA12CA7CA9CA14CA1
SCHEMBL404485 0.94 CA12 (0.89) CA12CA7CA9CA14CA1
SCHEMBL404484 0.94 CA12 (0.89) CA12CA7CA9CA14CA1
SCHEMBL71224 0.92 CA12 (0.84) CA12CA7CA9CA14CA1
SCHEMBL5057418 0.92 CA12 (0.84) CA12CA7CA9CA14CA1
SCHEMBL16024183 0.91 CA12 (0.83) CA12CA7CA9CA14CA1
SCHEMBL17061331 0.91 CA12 (0.83) CA12CA7CA9CA14CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119875442-B Fluorocarbon powder coating and preparation method thereof 金华市大友谊塑粉科技有限公司 2025-06-03 CN claimed
CN-119326786-B High-resistance starch composition for improving diabetes and preparation method thereof 中国热带农业科学院热带生物技术研究所 2025-05-23 CN claimed
CN-119875442-A Fluorocarbon powder coating and preparation method thereof 金华市大友谊塑粉科技有限公司 2025-04-25 CN claimed
CN-119390573-A Hydroxycinnamic acid derivative and preparation method and application thereof 重庆医科大学 2025-02-07 CN claimed
CN-119326786-A High-resistance starch composition for improving diabetes and preparation method thereof 中国热带农业科学院热带生物技术研究所 2025-01-21 CN claimed
CN-118666843-A Quinolone-lixiviated histone deacetylase inhibitor and preparation method and application thereof 天津市医药科学研究所(天津市医药与健康研究中心) 2024-09-20 CN claimed
CN-118084732-A 5-HTT/HDAC targeted double-target inhibitor and preparation method and application thereof 杭州师范大学 2024-05-28 CN claimed
CN-117942328-A Application of methyl 4-hydroxy cinnamate in preparation of medicines for treating inflammatory diseases 新乡医学院 2024-04-30 CN claimed
CN-117924281-A Reversible light response compound, preparation method and application thereof, self-assembly system, graphene composition and photoelectric functional device 中国石油化工股份有限公司 2024-04-26 CN claimed
CN-117304043-A Esmolol hydrochloride and preparation of preparation thereof 杭州沐源生物医药科技有限公司 2023-12-29 CN claimed
CN-104356087-A Novel nitric oxide donor type HDAC (histone deacetylase) inhibitor as well as preparation method and medical application thereof AFFILIATED HOSPITAL OF NANTONG UNIV 2015-02-18 CN claimed
US-8784930-B2 Transparent conductive film having high optical transmittance and method for manufacturing the same FAR EASTERN NEW CENTURY CORPORATION (TW) 2014-07-22 US claimed
US-20120080218-A1 TRANSPARENT CONDUCTIVE FILM HAVING HIGH OPTICAL TRANSMITTANCE AND METHOD FOR MANUFACTURING THE SAME FAR EASTERN NEW CENTURY CORPORATION (TW) 2012-04-05 US claimed
EP-0980203-B1 ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES SQUIRES MERYL (US) 2007-04-04 EP claimed
EP-0980203-A4 ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES SQUIRES MERYL (US) 2004-05-06 EP claimed
US-20030104082-A1 Antimicrobial prevention and treatment of human immunedeficience virus and other infectious diseases MCGINLEY PARTNERS, LLC (US) 2003-06-05 US claimed
EP-0980203-A1 ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES Squires, Meryl (US) 2000-02-23 EP claimed
WO-1998042188-A1 ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES SQUIRES MERYL (US) 1998-10-01 WO claimed
US-5243021-A Polylactam, polyester, polyether copolymers containing stilbene groups LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1993-09-07 US claimed
EP-0003461-B1 AMINOALCOHOL DERIVATIVES OF ORTHO-HYDROXY-METHYL CINNAMATE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1981-04-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030104082-A1 Antimicrobial prevention and treatment of human immunedeficience virus and other infectious diseases CD14, CD59, SLC19A1 CA12 3378/4885CA7 3310/4885CA9 2899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.