SCHEMBL547439

SCHEMBL547439

Cc1cc(O)ccc1C=CC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.64
ESR1 P03372 3/20 0.55
TYR P14679 3/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA4 P22748 2/20 0.50
CA12 O43570 1/20 0.50
AKR1B10 O60218 1/20 0.50
CA3 P07451 1/20 0.50
PKM P14618 1/20 0.50
AKR1B1 P15121 1/20 0.50
CA6 P23280 1/20 0.50
DPP4 P27487 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
HCAR2 Q8TDS4 1/20 0.50
ESR2 Q92731 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547437 1.00 MIF (0.64) MIFESR1TYRCA1CA2
SCHEMBL10021706 0.87 CAPN1 (0.50) MIFTYRNFKB1CHRNA7APP
SCHEMBL18517696 0.85 MAPT (0.50) MIFTYRCHRNA7APPBACE1
SCHEMBL584566 0.83 CYP1A1 (0.55) MIFESR1CA1CA2CA4
SCHEMBL30278658 0.83 CYP1A1 (0.55) MIFESR1CA1CA2CA4
SCHEMBL584565 0.83 CYP1A1 (0.55) MIFESR1CA1CA2CA4
SCHEMBL27882901 0.82 TYR (0.72) TYRPKMNFKB1CHRNA7ALDH1A1
SCHEMBL28116621 0.82 TYR (0.72) TYRPKMNFKB1CHRNA7ALDH1A1
SCHEMBL28391865 0.81 MIF (0.68) MIFESR1TYRCA1CA2
SCHEMBL471946 0.81 MIF (0.68) MIFESR1TYRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025081932-A1 RETINOL DERIVATIVE OR SALT THEREOF, AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 深圳市护家科技有限公司 2025-04-24 WO claimed
CN-119841755-A Retinol derivative or its salt, and preparation method and application thereof 深圳市护家科技有限公司 2025-04-18 CN claimed
EP-3191839-B1 METHODS FOR INHIBITING HMGB1 ACTIVATION OF MELANOCYTES, METHOD FOR IDENTIFICATION OF AGENTS SUITABLE FOR SUCH INHIBITON PROCTER & GAMBLE (US) 2019-07-24 EP claimed
EP-3191839-A1 METHODS FOR INHIBITING HMGB1 ACTIVATION OF MELANOCYTES, METHOD FOR IDENTIFICATION OF AGENTS SUITABLE FOR SUCH INHIBITON The Procter and Gamble Company (US) 2017-07-19 EP claimed
WO-2016040242-A1 METHODS FOR INHIBITING HMGB1 ACTIVATION OF MELANOCYTES, METHOD FOR IDENTIFICATION OF AGENTS SUITABLE FOR SUCH INHIBITON THE PROCTER & GAMBLE COMPANY (US) 2016-03-17 WO claimed
US-20160077082-A1 COMPOSITIONS AND METHODS FOR INHIBITING HMGB1 ACTIVATION OF MELANOCYTES THE PROCTER & GAMBLE COMPANY 2016-03-17 US claimed
EP-0980203-B1 ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES SQUIRES MERYL (US) 2007-04-04 EP claimed
EP-0980203-A4 ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES SQUIRES MERYL (US) 2004-05-06 EP claimed
US-20030104082-A1 Antimicrobial prevention and treatment of human immunedeficience virus and other infectious diseases MCGINLEY PARTNERS, LLC (US) 2003-06-05 US claimed
EP-0980203-A1 ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES Squires, Meryl (US) 2000-02-23 EP claimed
WO-1998042188-A1 ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES SQUIRES MERYL (US) 1998-10-01 WO claimed
EP-0003461-B1 AMINOALCOHOL DERIVATIVES OF ORTHO-HYDROXY-METHYL CINNAMATE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1981-04-29 EP claimed
WO-2025081932-A1 RETINOL DERIVATIVE OR SALT THEREOF, AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 深圳市护家科技有限公司 2025-04-24 WO disclosed
CN-119841755-A Retinol derivative or its salt, and preparation method and application thereof 深圳市护家科技有限公司 2025-04-18 CN disclosed
CN-111602087-B Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, polymer and compound JSR株式会社 2023-03-24 CN disclosed
CN-115103907-A Compositions and methods for enhancing immune activity 金橘生物科技公司 2022-09-23 CN disclosed
US-4210577-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, phosphonic acid ester and phenol ARGUS CHEMICAL CORPORATION (US) 1980-07-01 US disclosed
US-4209431-A OXIDATION AND HEAT RESISTANCE WITCO CHEMICAL CORPORATION (US) 1980-06-24 US disclosed
US-4080364-A Stabilization of polyolefins against degradative deterioration as a result of exposure to light and air at elevated temperatures ARGUS CHEMICAL CORPORATION (US) 1978-03-21 US disclosed
US-3997551-A OXIDATION RESISTANCE, STABILIZE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030104082-A1 Antimicrobial prevention and treatment of human immunedeficience virus and other infectious diseases CD14, CD59, SLC19A1 MIF 16/4885ESR1 2967/4885TYR 2456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.