Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.66 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL28004393 | 0.96 | GABRA1 (0.61) | GABRA1GABRB2POLBMAPTKMT2A | |
| SCHEMBL472482 | 0.84 | GABRA1 (0.50) | GABRA1GABRB2POLBMAPTKMT2A | |
| SCHEMBL8665741 | 0.81 | LMNA (0.41) | GABRA1GABRB2POLBMAPTKMT2A | |
| SCHEMBL9245228 | 0.80 | GABRA1 (0.41) | GABRA1GABRB2POLBMAPTKMT2A | |
| SCHEMBL789209 | 0.80 | ERN1 (0.52) | GABRA1GABRB2POLBTSHRGFER | |
| SCHEMBL7131922 | 0.79 | KMT2A (0.40) | GABRA1GABRB2POLBMAPTKMT2A | |
| SCHEMBL11223610 | 0.79 | LMNA (0.40) | GABRA1GABRB2POLBMAPTKMT2A | |
| SCHEMBL252293 | 0.79 | GABRA1 (1.00) | GABRA1GABRB2POLBMAPTKMT2A | |
| SCHEMBL71514 | 0.79 | GABRA1 (0.70) | GABRA1GABRB2POLBMAPTKMT2A | |
| SCHEMBL30893166 | 0.79 | GABRA1 (0.70) | GABRA1GABRB2POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053935-B | Novel macromolecular self-supported salicylaldimine metal titanium complex, and synthesis method and use method thereof | 武汉科技大学 | 2022-02-01 | — | — | CN | claimed |
| EP-1678112-A1 | METHOD FOR PRODUCTION OF BIS(HYDROXY-AROMATIC) COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2006-07-12 | — | — | EP | claimed |
| WO-2005040080-A1 | METHOD FOR PRODUCTION OF BIS(HYDROXY-AROMATIC) COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2005-05-06 | — | — | WO | claimed |
| US-6833482-B1 | Catalytic reductive coupling reaction using hydrogen as the reductant | GENERAL ELECTRIC COMPANY | 2004-12-21 | — | — | US | claimed |
| CN-112321452-B | Magnolol derivative, honokiol derivative and hydrochloride thereof, preparation method and application | 北京红惠新医药科技有限公司 | 2022-11-29 | — | — | CN | disclosed |
| WO-2022052998-A1 | MAGNOLOL DERIVATIVE, MAGNOLOL DERIVATIVE AND SALTS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 北京红惠新医药科技有限公司 | 2022-03-17 | — | — | WO | disclosed |
| CN-109053935-B | Novel macromolecular self-supported salicylaldimine metal titanium complex, and synthesis method and use method thereof | 武汉科技大学 | 2022-02-01 | — | — | CN | disclosed |
| CN-112321452-A | Magnolol derivative, honokiol derivative and hydrochloride thereof, preparation method and application | 北京红惠新医药科技有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-110982537-A | Polymerizable compound, and liquid crystal composition and liquid crystal display element using same | DIC株式会社 | 2020-04-10 | — | — | CN | disclosed |
| EP-3135272-A1 | COMPOSITIONS FOR MOUTH WASH IN THE FORM OF TABLETS | BASF S.A. (BR) | 2017-03-01 | — | — | EP | disclosed |
| US-8110601-B2 | Compound, α1 adrenergic receptor antagonistic agent, and composition | SUNTORY HOLDINGS LIMITED (JP) | 2012-02-07 | — | — | US | disclosed |
| US-8110601-B2 | Compound, α1 adrenergic receptor antagonistic agent, and composition | SUNTORY HOLDINGS LIMITED (JP) | 2012-02-07 | — | — | US | disclosed |
| US-4883613-A | TREATMENT OF RHEUMATOID ARTHRITIS, IMMUNOSUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1989-11-28 | — | — | US | disclosed |
| US-4883614-A | TREATMENT OF RHEUMATOID ARTHRITIS, IMMUNOSUPPRESSANTS | HOFFMAN-LA ROCHE INC. (US) | 1989-11-28 | — | — | US | disclosed |
| US-4780251-A | ANTIRHEUMATIC AGENTS, IMMUNOSUPPRESSANTS | HOFFMAN-LA ROCHE INC. (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0169571-B1 | PHENYLNONATETRAENIC-ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-03-09 | — | — | EP | disclosed |
| US-4648996-A | ANTIRHEUMATIC AGENTS, IMMUNOSUPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1987-03-10 | — | — | US | disclosed |
| EP-0169571-A1 | Phenylnonatetraenic-acid derivatives, their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-01-29 | — | — | EP | disclosed |
| EP-0132651-A2 | Use of cyclic phenol organosilane ester | HÜLS AKTIENGESELLSCHAFT (DE) | 1985-02-13 | — | — | EP | disclosed |
| US-4011321-A | 6-(3-SUBSTITUTED AMINO-2-HYDROXYPROPOXYARYL)-4,5-DIHYDRO-3(2H)-PYRIDAZINONES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-03-08 | — | — | US | disclosed |