SCHEMBL5475258

SCHEMBL5475258

c1ccc2c(c1)c1ccccc1c1nc3c4ccccc4c4ccccc4c3cc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.41
MAPT P10636 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
PKM P14618 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 6/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MYC P01106 1/20 0.40
MAX P61244 1/20 0.40
TRPM4 Q8TD43 1/20 0.39
HSD17B10 Q99714 4/20 0.38
CYP2A6 P11509 1/20 0.38
TSHR P16473 1/20 0.38
HPGD P15428 2/20 0.38
HIF1A Q16665 1/20 0.38
CYP1B1 Q16678 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668870 0.84 ALDH1A1 (0.50) HPRT1MAPTTDP1LMNAMEN1
SCHEMBL17523386 0.84 ALDH1A1 (0.52) MAPTTDP1LMNAMEN1KMT2A
SCHEMBL16081603 0.83 ALDH1A1 (0.55) MAPTTDP1LMNAMEN1KMT2A
SCHEMBL16169847 0.82 LMNA (0.40) MAPTTDP1LMNAMEN1POLB
SCHEMBL30471900 0.81 MAPT (0.48) HPRT1MAPTTDP1LMNAMEN1
SCHEMBL11795067 0.81 MAPT (0.48) HPRT1MAPTTDP1LMNAMEN1
SCHEMBL12355748 0.81 MAPT (0.48) HPRT1MAPTTDP1LMNAMEN1
SCHEMBL16204041 0.78 ALDH1A1 (0.42) MAPTTDP1LMNAMEN1POLB
SCHEMBL29470804 0.78 ALDH1A1 (0.54) MAPTTDP1LMNAPOLBKMT2A
SCHEMBL730399 0.78 ALDH1A1 (0.54) MAPTTDP1LMNAPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed