SCHEMBL547586

SCHEMBL547586

Clc1cccc(COCc2cccc(Cl)c2Cl)c1Cl

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.69
PNMT P11086 2/20 0.60
TAAR1 Q96RJ0 1/20 0.54
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46
AR P10275 1/20 0.45
CYP2A13 Q16696 2/20 0.43
CARM1 Q86X55 1/20 0.41
TSHR P16473 1/20 0.41
DBH P09172 1/20 0.40
KMT2A Q03164 1/20 0.39
CYP1A2 P05177 1/20 0.39
GLA P06280 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9511260 0.87 IDO1 (0.60) IDO1PNMTTAAR1ALDH1A1KDM4E
SCHEMBL3156120 0.87 IDO1 (0.60) IDO1PNMTTAAR1ALDH1A1KDM4E
SCHEMBL995345 0.86 IDO1 (0.69) IDO1PNMTTAAR1ALDH1A1KDM4E
SCHEMBL4727378 0.84 IDO1 (0.56) IDO1PNMTTAAR1ALDH1A1KDM4E
SCHEMBL12877184 0.84 IDO1 (0.67) IDO1PNMTTAAR1ALDH1A1KDM4E
SCHEMBL1145312 0.82 IDO1 (0.64) IDO1PNMTTAAR1ALDH1A1KDM4E
SCHEMBL1145314 0.82 IDO1 (0.64) IDO1PNMTTAAR1ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL1715086 0.80 IDO1 (1.00) IDO1PNMTTAAR1CYP3A4
SCHEMBL3774965 0.80 IDO1 (0.67) IDO1PNMTTAAR1TSHR
SCHEMBL1683184 0.79 IDO1 (0.60) IDO1PNMTTAAR1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110073507-B Organic semiconductor composition, organic thin film, and organic thin film transistor 日本化药株式会社 2023-07-04 CN disclosed
CN-112834640-B Method for separating and detecting components in permethrin 上海汉维生物医药科技有限公司 2022-08-30 CN disclosed
CN-114227834-A Processing method of insect-proof and moisture-proof wood board 彩智科技商贸(深圳)有限公司 2022-03-25 CN disclosed
US-8586020-B2 Poly(organophosphazene) composition for biomaterials KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-11-19 US disclosed
EP-2538780-A1 ESTROGEN RECEPTOR LIGANDS AND METHODS OF USE THEREOF Gtx, Inc. (US) 2013-01-02 EP disclosed
EP-2455362-A1 Nuclear receptor binding agents GTX, Inc. (US) 2012-05-23 EP disclosed
US-8158828-B2 Nuclear receptor binding agents GTX, INC. (US) 2012-04-17 US disclosed
US-8110203-B2 Adjuvant comprising non-toxic cross-linked muramyl dipeptide (MDP) microparticles derived from Propionibacterium acnes INNATE THERAPEUTICS LIMITED (NZ) 2012-02-07 US disclosed
WO-2011106317-A1 ESTROGEN RECEPTOR LIGANDS AND METHODS OF USE THEREOF GTX, INC. (US) 2011-09-01 WO disclosed
WO-2009033689-A1 PIPERIDONE DERIVATIVES AND MEDICAL USES THEREOF HEINRICH-PETTE-INSTITUT (DE) 2009-03-19 WO disclosed
EP-0276279-A1 COMPOSITION OF MATTER AND METHOD OF IMMUNIZING AGAINST VIRAL CAUSATIVE AGENTS OF AIDS AND ARC SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH (US) 1988-08-03 EP disclosed
US-4751064-A POLYPEPTIDE, HIGH MOLECULAR WEIGHT CARRIER YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) 1988-06-14 US disclosed
WO-1988000471-A1 COMPOSITION OF MATTER AND METHOD OF IMMUNIZING AGAINST VIRAL CAUSATIVE AGENTS OF AIDS AND ARC SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH (US) 1988-01-28 WO disclosed
EP-0245362-A1 SYNTHETIC PEPTIDES AND USE FOR DIAGNOSIS AND VACCINATION FOR AIDS AND ARC. SOUTHWEST FOUND BIOMED RES (US) 1987-11-19 EP disclosed
WO-1987002775-A1 SYNTHETIC PEPTIDES AND USE FOR DIAGNOSIS AND VACCINATION FOR AIDS AND ARC SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH (US) 1987-05-07 WO disclosed
EP-0082789-B1 IMMUNOLOGICAL COMPOSITION AND METHOD FOR HEPATITIS B VIRUS Baylor College of Medicine (US) 1987-04-08 EP disclosed
US-4444682-A OF HYDROXY AMINO ACIDS OR PEPTIDES CONTAINING SAME THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1984-04-24 US disclosed
EP-0082789-A2 Immunological composition and method for hepatitis B virus Baylor College of Medicine (US) 1983-06-29 EP disclosed
US-4387253-A Preparation of dichlorobenzyl alcohol THE BOOTS COMPANY LIMITED (GB) 1983-06-07 US disclosed
EP-0047622-A1 Preparation of dichlorobenzyl alcohol The Boots Company PLC (GB) 1982-03-17 EP disclosed