SCHEMBL995345

SCHEMBL995345

Clc1cccc(COOCc2cccc(Cl)c2Cl)c1Cl

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.69
PNMT P11086 2/20 0.60
TAAR1 Q96RJ0 1/20 0.54
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46
CYP2A13 Q16696 2/20 0.43
CARM1 Q86X55 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
ALOX12 P18054 1/20 0.40
DBH P09172 1/20 0.40
GLA P06280 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547586 0.86 IDO1 (0.69) IDO1PNMTTAAR1ALDH1A1KDM4E
SCHEMBL12877184 0.84 IDO1 (0.67) IDO1PNMTTAAR1ALDH1A1KDM4E
SCHEMBL3156120 0.83 IDO1 (0.60) IDO1PNMTTAAR1ALDH1A1KDM4E
SCHEMBL1145314 0.82 IDO1 (0.64) IDO1PNMTTAAR1ALDH1A1KDM4E
SCHEMBL1145312 0.82 IDO1 (0.64) IDO1PNMTTAAR1ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL1715086 0.80 IDO1 (1.00) IDO1PNMTTAAR1CYP3A4
SCHEMBL8762708 0.80 IDO1 (0.67) IDO1PNMTTAAR1TSHR
SCHEMBL1683184 0.79 IDO1 (0.60) IDO1PNMTTAAR1ALDH1A1KDM4E
SCHEMBL9511260 0.79 IDO1 (0.60) IDO1PNMTTAAR1ALDH1A1KDM4E
SCHEMBL1547863 0.78 PNMT (0.62) IDO1PNMTTAAR1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4090714-A1 NON-POROUS MICROPARTICLES Covestro (Netherlands) B.V. (NL) 2022-11-23 EP disclosed
US-20110273093-A1 ENCAPSULATED COMPACT FLUORESCENT BULBS AND ARTICLES AND METHODS OF MANUFACTURE CALDWELL GREGORY 2011-11-10 US disclosed
WO-2011006089-A2 COATED GLASS BOTTLES, ENCAPSULATED COMPACT FLUORESCENT BULBS AND ARTICLES AND METHODS OF MANUFACTURE GREG CALDWELL COMPANY, LLC (US) 2011-01-13 WO disclosed
EP-1419205-B1 LOW GLOSS FREE RADICAL POWDER COATINGS DU PONT (US) 2007-01-10 EP disclosed
US-20060241248-A1 Glazing joint EYE-BOND LIMITED (GB) 2006-10-26 US disclosed
EP-1565537-A1 GLAZING JOINT Foreman, Paul David (GB) 2005-08-24 EP disclosed
WO-2004039908-A1 GLAZING JOINT FOREMAN PAUL DAVID (GB) 2004-05-13 WO disclosed
JP-2000283369-A POLYOLEFIN JOINT OSAKA GAS CO LTD 2000-10-13 JP disclosed
US-5880209-A POLYESTERURETHANE COPOLYMERS WITH NEUTRALIZED ACID GROUPS HERBERTS GMBH (DE) 1999-03-09 US disclosed
US-5342882-A Polyurethane resin-based binder HERBERTS GMBH (DE) 1994-08-30 US disclosed
US-5034423-A Inorganic-organic flame-retardant polyols BLOUNT DAVID H (US) 1991-07-23 US disclosed
US-4981885-A PAINTS HOECHST AG (DE) 1991-01-01 US disclosed
US-4965660-A HIGH RELIABILITY, STABILITY, SHOCKPROOF HITACHI, LTD. (JP) 1990-10-23 US disclosed
US-4841331-A SUBSTRATE COATED WITH COPOLYMER OF FLUOROOLEFIN AND UNSATURATED SILICON COMPOUND; STABILITY RICOH COMPANY, LTD. (JP) 1989-06-20 US disclosed
EP-0137385-B1 INTEGRATED CIRCUIT PACKAGE (1111111) HITACHI, LTD. (JP) 1988-03-02 EP disclosed
EP-0137385-A1 Integrated circuit package (1111111) HITACHI, LTD. (JP) 1985-04-17 EP disclosed
US-4425472-A WATER IN OIL EMULSIONS LORD CORPORATION (US) 1984-01-10 US disclosed
US-4205154-A Triallyl carbonate polymers PPG INDUSTRIES, INC. (US) 1980-05-27 US disclosed
US-4144262-A ALLYL POLYMERS FOR OPTICAL USES PPG INDUSTRIES, INC. (US) 1979-03-13 US disclosed
US-4043982-A ADHESIVES, SEALANTS, POTTING COMPOUNDS LOCTITE (IRELAND) LIMITED (EI) 1977-08-23 US disclosed