Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.60 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547586 | 0.87 | IDO1 (0.69) | IDO1PNMTTAAR1ARKDM4E | |
| SCHEMBL6507641 | 0.83 | IDO1 (0.57) | IDO1PNMTTAAR1ALDH1A1KMT2A | |
| SCHEMBL21937776 | 0.81 | IDO1 (0.39) | IDO1TAAR1KDM4EPOLBALDH1A1 | |
| SCHEMBL15771305 | 0.81 | IDO1 (0.43) | IDO1PNMTTAAR1KDM4EPOLB | |
| Ether SCHEMBL28856080 | 0.81 | KDM4E (0.47) | IDO1PNMTTAAR1KDM4EPOLB | |
| SCHEMBL3156120 | 0.80 | IDO1 (0.60) | IDO1PNMTTAAR1ARKDM4E | |
| SCHEMBL12949882 | 0.79 | IDO1 (0.42) | IDO1TAAR1KDM4EALDH1A1MAPT | |
| SCHEMBL1145314 | 0.79 | IDO1 (0.64) | IDO1PNMTTAAR1ARKDM4E | |
| SCHEMBL995345 | 0.79 | IDO1 (0.69) | IDO1PNMTTAAR1KDM4EPOLB | |
| SCHEMBL4727378 | 0.77 | IDO1 (0.56) | IDO1PNMTTAAR1ARKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564509-A1 | PROCESS FOR PRODUCING DIHYDROPYRIDINE CARBOXYLIC ACIDS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992011239-A1 | PROCESS FOR PRODUCING DIHYDROPYRIDINE CARBOXYLIC ACIDS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-07-09 | — | — | WO | disclosed |